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Table 1 Baseline characteristics of 205 patients stratified by a 2-hour OGTT

From: Dysglycemia and increased left ventricle mass in normotensive patients admitted with a first myocardial infarction: prognostic implications of dysglycemia during 14 years of follow-up

 

NGT

IFG/IGT

New T2DM

Known T2DM

P

Patients, n (%)

85 (41)

70 (34)

38 (19)

12 (6)

 

Age (years)

60 ± 12

60 ± 13

65 ± 11

63 ± 8

NS

Follow-up (years)

10 ± 3

10 ± 3

10 ± 4

11 ± 2

NS

Men, n (%)

72 (85)

59 (84)

23 (61)

10 (83)

0.04

STEMI, n (%)

50 (59)

43 (61)

22 (58)

8 (67)

NS

SBP (mmHg)

139 ± 27

136 ± 26

143 ± 30

119 ± 25

NS

DBP (mmHg)

86 ± 20

84 ± 18

81 ± 16

76 ± 19

NS

BMI (g/m2)

26 ± 5

27 ± 4

26 ± 5

28 ± 5

NS

Current Smoker, n (%)

47 (55)

46 (66)

20 (53)

5 (42)

NS

Medication:

 ASA, n (%)

12 (14)

8 (11)

5 (13)

2 (18)

NS

 Statins, n (%)

66 (78)

60 (86)

32 (84)

10 (83)

NS

 Biguanides, n (%)

0 (0)

0 (0)

0 (0)

3 (27)

N/A

 Insulin, n (%)

0 (0)

0 (0)

0 (0)

4 (36)

N/A

Blood samples:

 HbA1c (%)

5.5 ± 0.3

5.6 ± 0.4

6.0 ± 1.2

7.6 ± 1.4

<  0.001

 Fasting glucose (mmol/l)

4.7 ± 0,5

5.1 ± 0.6

6.2 ± 1.9

N/A

<  0.001

 2-hour glucose (mmol/l)

6.3 ± 1.1

8.6 ± 1.0

11.7 ± 2.9

N/A

<  0.001

 LDL (mmol/L)

3.1 ± 1.0

2.8 ± 0.8

2.5 ± 0.8

2.4 ± 0.6

0.01

 HDL (mmol/L)

1.2 ± 0.4

1.1 ± 0.3

1.1 ± 0.4

1.1 ± 0.3

NS

 Total cholesterol (mmol/L)

5.0 ± 1.2

4.7 ± 1.0

4.3 ± 1.0

4.0 ± 0.8

0.01

 Triglyceride (mmol/L)

1.5 ± 0.9

1.6 ± 1.0

1.5 ± 0.8

1.3 ± 0.6

NS

Echocardiographic examination:

 LVM (g/m2)

102 ± 36

111 ± 42

123 ± 61

138 ± 56

0.02

 LVH, n (%)

21 (25)

26 (37)

16 (42)

8 (67)

0.01

 IVS (cm)

1.0 ± 0.2

1.1 ± 0.3

1.1 ± 0.3

1.2 ± 0.3

0.03

 LVID (cm)

4.9 ± 0.7

5.0 ± 0.9

5.0 ± 0.8

5.1 ± 0.4

NS

 LVPW (cm)

1.1 ± 0.3

1.1 ± 0.3

1.1 ± 0.3

1.2 ± 0.2

NS

 LVEF (%)

52 ± 11

51 ± 12

50 ± 12

54 ± 8

NS

 E/A ratio

1.2 ± 0.5

1.2 ± 0.7

1.0 ± 0.4

1.5 ± 1.4

NS

  1. OGTT oral glucose tolerance test, NGT normal glucose tolerance, IFG/IGT impaired fasting glucose/impaired glucose tolerance, New T2DM newly detected type 2 diabetes mellitus, Known T2DM known type 2 diabetes mellitus, STEMI ST-segment elevation myocardial infarction, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, ASA acetylsalicylic acid, HbA1c hemoglobin A1c, LDL low density lipoprotein, HDL high density lipoprotein, LVM left ventricle mass, LVH left ventricle hypertrophy, IVS inter ventricular septum thickness, LVID left ventricle internal diameter, LVPW left ventricle posterior wall thickness, LVEF left ventricle ejection fraction, E/A ratio early to late ventricular filling velocity ratio, N/A not applicable, NS not significant