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Table 1 Clinical and laboratory characteristics of the subjects in different groups

From: Serum ferritin, an early marker of cardiovascular risk: a study in Chinese men of first-degree relatives with family history of type 2 diabetes

Variable

 

P

Group A

n = 59

Group B

n = 57

Group C

n = 60

Group D

n = 56

SF

FH

SF*FH

age (y)

49.61 ± 11.16

51.21 ± 11.71

50.44 ± 11.28

50.03 ± 10.81

0.718

0.917

0.541

BMI (kg/m2)

23.73 ± 2.64

25.34 ± 2.78

24.71 ± 4.21

25.83 ± 3.39

0.010

0.165

0.643

WC (cm)

86.50 ± 9.76

91.16 ± 10.20

89.48 ± 12.30

92.67 ± 11.13

0.030

0.213

0.680

SBP (mmHg)

113.0 ± 16.68

132.16 ± 22.73

129.67 ± 17.43

133.43 ± 21.27

< 0.001

0.003

0.011

DBP (mmHg)

82.19 ± 9.32

78.63 ± 9.17

82.59 ± 9.49

87.29 ± 11.81

0.725

0.006

0.012

FPG (mmol/L)

5.86 ± 0.63

6.51 ± 0.87

5.83 ± 0.81

6.77 ± 0.75

< 0.001

0.348

0.239

PPG-2 h (mmol/L)

7.92 ± 2.38

8.81 ± 2.61

7.47 ± 2.61

10.49 ± 3.61

< 0.001

0.186

0.022

FINS (uIU/ml)

9.22 ± 3.42

13.10 ± 5.67

10.09 ± 2.83

15.19 ± 7.85

< 0.001

0.013

0.498

TG (mmol/L)(IQR)

1.53(0.51,6.63)

1.61(0.67,6.63)

1.20(0.51,11.89)

1.79(0.50,10.52)

0.975

0.720

0.939

HDL-C (mmol/L)

1.36 ± 0.32

1.27 ± 0.37

1.31 ± 0.33

1.23 ± 0.67

0.084

0.359

0.919

HOMA-IR

0.35 ± 0.19

0.52 ± 0.24

0.40 ± 0.16

0.60 ± 0.23

0.015

0.391

0.843

HOMA-β

1.87 ± 0.19

1.90 ± 0.30

1.94 ± 0.16

1.93 ± 0.22

0.891

0.494

0.785

SF (ng/ml) (IQR)

72.90

(49.95,93.75)

151.95

(116.60,219.88)

79.92

(60.90,91.57)

163.90

(129.98,224.50)

   
  1. Values are expressed as means ± SD, TG and SF were non-normally distributed, they were ln-transformed for analysis and are expressed as medians (IQR). FINS, HOMA- β and HOMA-IR were non-normally distributed, they were ln transformed for analysis. Two-way ANOVA was performed to assess the main effect of SF and FH and the interaction between them. Group A consisted of 59 low SF adults without family history; group B consisted of 57 high SF adults without family history; group C consisted of 60 low SF adults with family history; group D consisted of 56 high SF adults with family history. BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; FPG: fasting plasma glucose; PPG-2 h: postprandial plasma glucose 2 h; FINS: fasting insulin; TG: triglycerides; HDL-C: high density lipoprotein cholesterol; HOMA: homeostasis model assessment; SF: serum ferritin; FH: family history