Prior coronary artery disease | No prior coronary artery disease | p | |||
---|---|---|---|---|---|
n = 7219 | n = 21,185 | ||||
Missing data | Missing data | ||||
Male (n (%)) | 5785 (80) | 0 (0) | 15,277 (72) | 0 (0) | < 0.001 |
Mean age (years (SD)) | 67 (10) | 0 (0) | 62 (10) | 0 (0) | < 0.001 |
Prior coronary artery disease (n (%)) | |||||
Myocardial infarction | 5638 (78) | 29 (0.4) | |||
Percutaneous coronary intervention | 5072 (70) | 58 (0.8) | |||
Coronary artery bypass grafting | 2228 (31) | 9 (0.1) | |||
Smoking (n (%)) | 408 (6) | 1048 [5] | < 0.001 | ||
Never smoked | 1417 [20] | 5339 (25) | < 0.001 | ||
Ex-smoker | 3067 (43) | 6290 (30) | < 0.001 | ||
Smoker | 2327 (32) | 8508 (40) | < 0.001 | ||
Antihypertensive treatment (n (%)) | 4262 (59) | 43 (0.6) | 8055 (38) | 38 (0.2) | < 0.001 |
Diabetes (n (%)) | 2169 (30) | 8 (0.1) | 3052 (14) | 13 (0.1) | < 0.001 |
Medication prior to admission (n (%)) | |||||
Acetylsalicylic acid | 5753 (80) | 95 (1) | 3668 (17) | 176 (1) | < 0.001 |
Statins | 5353 (74) | 110 (2) | 4013 (19) | 186 (1) | < 0.001 |
Beta blockers | 4720 (65) | 131 (2) | 2888 [14] | 263 (1) | < 0.001 |
ACE/AII receptor inhibitors | 3599 (50) | 110 (2) | 5474 (26) | 227 (1) | < 0.001 |
Diuretics | 1897 [26] | 110 (2) | 2752 [13] | 206 (1) | < 0.001 |
ST-elevation myocardial infarction (n (%)) | 1395 [19] | 235 (3) | 8185 (39) | 845 (4) | < 0.001 |
Median systolic blood pressure (mmHg (25th, 75th percentile)) | 140 (123, 159) | 251 (4) | 140 (124, 160) | 688 (3) | 0.02 |
Median diastolic blood pressure (mmHg (25th, 75th percentile)) | 80 (70, 90) | 251 (4) | 82 (72, 93) | 688 (3) | < 0.001 |
Median HbA1c (% (25th, 75th percentile)) if diabetes | 7.5 (6.6, 8.5) | 1116 (52) | 7.4 (6.6, 8.7) | 1493 (49) | 0.74 |
Median total cholesterol (mmol/L (25th, 75th percentile)) | 4.1 (3.5, 5.0) | 1809 [25] | 5.2 (4.4, 6.0) | 4534 (21) | < 0.001 |
Median LDL cholesterol (mmol/L (25th, 75th percentile)) | 2.3 (1.7, 3.0) | 2790 (39) | 3.4 (2.6, 4.1) | 7441 (35) | < 0.001 |
Median body mass index (kg/m2 (25th, 75th percentile) | 27.3 (24.7, 30.2) | 1323 [18] | 26.9 (24.5, 29.9) | 3265 (15) | 0.01 |