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Table 3 Longitudinal Data Analysis: Patient Report Outcomes Changes Over One year by Individual Characteristicsa

From: Association of sex, age and education level with patient reported outcomes in atrial fibrillation

 

Symptoms (β, 95% CI)

Anxiety (β, 95% CI)

Depression (β, 95% CI)

Function (β, 95% CI)

AF-related QOL (β, 95% CI)

Age Group

  > 18 and < 60

Ref

Ref

Ref

Ref

Ref

> 60 and < 70

 Baseline

−0.44 (− 0.78, − 0.12)

− 3.13 (− 5.19, 1.06)

−1.93 (− 4.08, − 0.86)

−1.04 (− 2.98, 0.90)

1.38 (− 5.11, 7.88)

 6 month

−0.73 (− 1.06, − 0.39)

−2.75 (− 4.94, − 0.56)

−3.12 (− 4.27, − 1.12)

−1.82 (− 3.88, 0.24)

2.16 (− 4.72, 9.04)

 12 month

−0.90 (− 1.24, − 0.56)

−3.63 (− 5.82, − 1.44)

− 2.93 (− 5.12, − 1.67)

−1.92 (− 3.97, 0.14)

9.54 (2.57, 16.52)

> 70 and < 80

 Baseline

−0.70 (− 1.01, − 0.38)

− 4.07 (− 6.05, − 2.09)

−2.74 (− 4.42, − 0.96)

−2.16 (− 4.07, − 0.25)

1.10 (−5.32, 7.51)

 6 month

−0.81 (− 1.14, − 0.49)

−3.05 (− 5.14, − 0.96)

−2.95 (− 4.82, − 1.09)

− 3.22 (− 5.22, − 1.23)

5.95 (− 0.66, 12.55)

 12 month

−0.87 (−1.19, − 0.54)

−3.68 (− 5.77, − 1.59)

− 2.74 (− 4.60, − 0.88)

− 3.71 (− 5.70, − 1.72)

2.42 (− 4.24, 9.08)

> 80

 Baseline

−0.80 (− 1.16, − 0.45)

−5.06 (− 7.31, − 2.81)

−3.79 (− 5.80, − 1.78)

− 6.24 (− 8.36, − 4.12)

0.27 (− 6.72, 7.25)

 6 month

−0.77 (− 1.13, − 0.40)

−4.59 (− 7.02, − 2.17)

− 2.67 (− 4.82, − 0.51)

−7.32 (− 9.60, − 5.04)

2.40 (− 5.12, 9.92)

 12 month

− 0.84 (− 1.21, − 0.48)

−4.46 (− 6.80, − 2.12)

− 2.94 (− 5.02, − 0.85)

−7.65 (− 9.88, − 5.41)

−1.23 (− 8.70, 6.25)

Female Sex

 Baseline

0.29 (0.13, 0.45)

2.08 (0.76, 3.40)

1.44 (0.25, 2.63)

−2.23 (− 3.52, − 0.94)

− 4.08 (− 8.06, − 0.10)

 6 Month

0.15 (− 0.07, 0.36)

2.28 (0.77, 3.80)

0.66 (−0.69, 2.01)

−2.94 (− 4.39, − 1.48)

0.17 (− 4.30, 4.64)

 12 Month

0.10 (− 0.05, 0.26)

1.82 (0.32, 3.32)

1.23 (− 0.11, 2.57)

− 3.18 (− 4.62, − 1.75)

0.29 (− 4.21, 4.80)

Education

  > than college

Ref

Ref

Ref

Ref

Ref

College

 Baseline

0.06 (−0.19, 0.32)

0.12 (− 1.48, 1.72)

0.26 (− 1.18, 1.70)

− 1.66 (− 3.26, − 0.06)

−0.66 (− 4.50, 3.18)

 6 month

− 0.01 (− 0.28, 0.25)

1.10 (− 0.70, 2.90)

0.91 (− 0.69, 2.51)

− 3.41 (− 5.16, − 1.66)

1.78 (− 3.79, 7.36)

 12 month

− 0.09 (− 0.36, 0.18)

0.40 (− 1.44, 2.25)

0.64 (− 1.00, 2.28)

− 3.28 (− 5.05, − 1.52)

1.66 (− 4.06, 7.37)

Some college

 Baseline

0.42 (0.17, 0.68)

1.86 (0.26, 3.45)

1.40 (−0.04, 2.84)

− 2.04 (− 3.63, − 0.44)

−4.41 (− 8.25, − 0.57)

 6 month

0.02 (− 0.25, 0.29)

2.71 (0.82, 4.61)

0.67 (− 1.01, 2.35)

− 2.66 (− 4.45, − 0.88)

−1.53 (− 7.19, 4.13)

 12 month

−0.04 (− 0.31, 0.23)

2.13 (0.33, 3.94)

0.73 (− 0.88, 2.34)

− 2.90 (− 4.63, − 1.16)

−1.39 (− 7.05, 4.27)

High School or less

 Baseline

0.02 (− 0.26, 0.31)

0.86 (−1.00, 2.71)

1.08 (− 0.58, 2.74)

− 2.86 (− 4.68, − 1.04)

−3.93 (− 6.88, 1.81)

 6 month

− 0.04 (− 0.35, 0.26)

1.30 (−0.91, 3.50)

0.35 (−1.61, 2.31)

−3.38 (− 5.47, − 1.29)

−0.87 (− 7.15, 5.41)

 12 month

−0.13 (− 0.44, 0.18)

0.69 (−1.47, 2.85)

0.94 (− 0.98, 2.86)

−3.63 (− 5.69, − 1.58)

1.33 (− 5.14, 7.81)

  1. aModel adjusted for the Charlson Comorbidity Index, body mass index, and rate and rhythm medication prescription
  2. Signficant results (p<0.05) are indicated by bold font