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Table 5 Prevalence Ratios for the Determinants of Hyperpolypharmacy

From: Prevalence and determinants of Hyperpolypharmacy in adults with heart failure: an observational study from the National Health and Nutrition Examination Survey (NHANES)

Variable

Univariate Model

Multivariable Model

 

PR (95% CI)

P-value

PR (95% CI)

P-value

Age ≥ 75

0.84 (0.62–1.14)

0.26

0.83 (0.63–1.11)

0.21

Women

1.22 (0.98–1.52)

0.07

1.15 (0.92–1.43)

0.23

Race

 White

Referent Group

 

Referent Group

 

 Black

0.96 (0.70–1.32)

0.81

0.98 (0.71–1.35)

0.91

 Other

0.56 (0.34–0.93)

0.03

0.59 (0.38–0.91)

0.02

Primary Payer

 Medicare without Medicaid

Referent Group

 

Referent Group

 

 Medicaid without Medicare

1.03 (0.60–1.76)

0.91

0.76 (0.48–1.21)

0.25

 Dual Medicare and Medicaid

1.03 (0.67–1.59)

0.88

0.82 (0.53–1.27)

0.37

 Other insurance

0.76 (0.39–1.48)

0.42

0.85 (0.50–1.45)

0.55

 Uninsured

0.40 (0.15–1.12)

0.08

0.66 (0.25–1.73)

0.40

Education, High school or below

1.95 (1.12–3.38)

0.02

1.74 (1.01–2.99)

0.04

Household Income

 ≥$75,000

Referent Group

 

Referent Group

 

 $35,000–$74,000

1.40 (0.80–2.45)

0.24

1.52 (0.89–2.59)

0.12

 $20,000–$34,000

1.48 (0.85–2.65)

0.17

1.42 (0.86–2.35)

0.16

 <$20,000

1.65 (1.00–2.70)

0.05

1.70 (1.01–2.85)

0.04

Not Married

0.87 (0.64–1.19)

0.38

0.82 (0.56–1.21)

0.32

Lives alone

0.89 (0.66–1.19)

0.43

0.95 (0.65–1.40)

0.81

Count of comorbidities

1.28 (1.21–1.36)

<0.001

1.19 (1.12–1.27)

<0.001

Smoking status

 Never

Referent Group

 

Referent Group

 

 Past

1.13 (0.85–1.50)

0.39

0.96 (0.72–1.28)

0.80

 Current

0.78 (0.42–1.46)

0.44

0.69 (0.41–1.16)

0.16

Change in self-reported health

 Better

Referent Group

 

Referent Group

 

 Same

0.86 (0.61–1.21)

0.39

1.08 (0.78–1.50)

0.64

 Worse

1.14 (0.76–1.70)

0.53

1.05 (0.72–1.53)

0.80

Cognitive impairment

1.10 (0.83–1.46)

0.52

0.92 (0.68–1.24)

0.57

Functional impairment

1.46 (1.03–2.06)

0.04

1.02 (0.72–1.45)

0.90

Number of contacts with ambulatory healthcare services, past year

 0–3

Referent Group

 

Referent Group

 

 4–9

2.78 (1.52–5.08)

0.001

2.20 (1.23–3.96)

0.01

 >10

4.31 (2.50–7.42)

<0.001

3.01 (1.73–5.21)

<0.001

Number of hospitalizations, past year

 <3

Referent Group

 

Referent Group

 

 ≥3

2.35 (1.75–3.14)

<0.001

1.70 (1.27–2.30)

0.001

Cycle Year

 2003–2004

Referent Group

 

Referent Group

 

 2005–2006

0.88 (0.55–1.40)

0.58

0.81 (0.50–1.33)

0.41

 2007–2008

1.15 (0.66–2.00)

0.63

1.16 (0.67–2.01)

0.60

 2009–2010

1.12 (1.72–1.76)

0.63

1.16 (0.79–1.71)

0.44

 2011–2012

1.13 (0.74–1.73)

0.57

1.16 (0.83–1.63)

0.38

 2013–2014

1.27 (0.70–2.31)

0.42

1.35 (0.88–2.06)

0.16

  1. Abbreviations: CI Confidence Interval, PR Prevalence Ratio