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Table 7 The three-dimensional interactions of the MMP9rs17576-TLR4rs11536889-TLR4rs1927914 with overall AA riska

From: The interaction effects between TLR4 and MMP9 gene polymorphisms contribute to aortic aneurysm risk in a Chinese Han population

SNP genotypes

  

P

OR(95%CI)

MMP9rs17576-TLR4rs11536889-TLR4rs1927914

GG + GA

GG

TT

 

1(ref)

GG + GA

GG

TC + CC

0.294

1.230(0.836–1.810)

GG + GA

GC + CC

TT

0.594

1.130(0.721–1.773)

GG + GA

GC + CC

TC + CC

0.942

0.982(0.594–1.622)

AA

GG

TT

0.844

0.887(0.268–2.932)

AA

GG

TC + CC

0.013

2.710(1.232–5.959)

AA

GC + CC

TT

0.152

2.484(0.715–8.635)

AA

GC + CC

TC + CC

0.086

3.312(0.843–13.012)

   

Pinteraction = 0.696, OR = 0.629(0.061–6.451)

  1. a, P for association was adjusted by age, gender, hypertension, diabetes and dyslipidemia