Table 4 Epistatic effect of pair-wise interacting factors of TLR4rs1927914 and MMP9rs17576 on the risk of AA subtypes^a

Comparison

Subset

P

OR(95%CI)

P

OR(95%CI)

P

OR(95%CI)

P

OR(95%CI)

TLR4rs1927914

MMP9rs17576

TC + CC vs. TT

GG + GA

0.244

1.247(0.860–1.809)

0.940

0.986(0.692–1.406)

0.902

1.025(0.687–1.531)

0.357

1.170(0.838–1.633)

MMP9rs17576

AA

0.686

1.266(0.403–3.985)

0.041(0.082^b)

6.329(1.077–37.184)

0.032(0.064^b)

6.554(1.172–36.649)

0.736

1.219(0.386–3.850)

MMP9rs17576

TLR4rs1927914

AA vs. GG + GA

TT

0.072

2.258(0.929–5.489)

0.202

0.369(0.080–1.706)

0.436

0.542(0.116–2.528)

0.150

1.890(0.794–4.496)

TLR4rs1927914

TC + CC

0.017(0.034^b)

2.519(1.177–5.389)

0.038(0.076^b)

2.322(1.047–5.150)

0.003(0.006^b)

3.243(1.488–7.068)

0.136

1.795(0.832–3.872)