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Table 5 Predictors of ischemic stroke in a multivariable Cox regression model within the late cohort (n = 24,227)

From: Increase in ticagrelor use over time is associated with lower rates of ischemic stroke following myocardial infarction

Variable HR (95% CI) P-value
Age 65–74 yearsa 2.16 (1.49–2.72) <0.001
Age ≥ 75 years 2.61 (1.96–3.49) <0.001
STEMIb 1.45 (1.2–1.76) <0.001
Diabetes 1.24 (1.03–1.5) 0.027
Hypertension 1.27 (1.04–1.55) 0.021
Atrial fibrillation 1.88 (1.55–2.27) <0.001
Heart failure during hospitalization 1.24 (1.03–1.55) 0.024
PCIc during hospitalization 0.68 (0.56–0.84) <0.001
Previous ischemic stroke 2.81 (2.29–3.5) <0.001
Statins at discharge 0.64 (0.51–0.8) <0.001
Ticagrelor at discharge 0.77 (0.63–0.94) <0.01
  1. aAge ≤ 64 years as reference for the different age categories
  2. bST-elevation myocardial infarction
  3. cPercutaneous coronary intervention