Skip to main content

Table 1 ORs (95% confidence intervals) for the associations between socioeconomic and demographic factors and first anticoagulant prescription among patients with NVAF

From: Sociodemographic factors and choice of oral anticoagulant in patients with non-valvular atrial fibrillation in Sweden: a population-based cross-sectional study using data from national registers

Patient characteristic

NOAC

Warfarin

Crude OR (95% CI)

Age- and sex-adjusted OR (95% CI)

Multivariable adjusted ORa (95% CI)

N = 18,638

N = 49,418

Sex

 Men

10,144 (54.4)

27,198 (55.0)

1.0 (ref)

1.0 (ref)

1.0 (ref)

 Women

8494 (45.6)

22,220 (45.0)

1.02 (0.99–1.06)

1.04 (1.01–1.08)

1.05 (1.01–1.10)

Age (years)

 Mean ± SD

74.4 ± 11.1

73.7 ± 10.7

   

 18–54

964 (5.2)

2431 (4.9)

0.98 (0.91–1.06)

0.99 (0.91–1.07)

0.88 (0.80–0.97)

 55–64

2488 (13.4)

6151 (12.5)

1.00 (0.95–1.06)

1.00 (0.95–1.06)

0.95 (0.88–1.02)

 65–74

6456 (34.6)

15,969 (32.3)

1.0 (ref)

1.0 (ref)

1.0 (ref)

 75–84

5630 (30.2

17,143 (34.7)

0.81 (0.78–0.85)

0.81 (0.78–0.84)

0.85 (0.81–0.90)

 ≥85

3100 (16.6)

7724 (15.6)

0.99 (0.94–1.04)

0.98 (0.93–1.03)

0.91 (0.85–0.97)

Regionb

 Urban

9181 (49.5)

23,608 (47.9)

1.0 (ref)

1.0 (ref)

1.0 (ref)

 South

3741 (20.2)

9821 (19.9

0.98 (0.94–1.02)

0.98 (0.94–1.03)

1.05 (1.00–1.14)

 Mid

3721 (20.1)

6455 (13.1)

1.48 (1.41–1.55)

1.48 (1.41–1.55)

1.67 (1.59–1.77)

 North

1890 (10.2)

9365 (19)

0.52 (0.49–0.55)

0.52 (0.49–0.55)

0.48 (0.45–0.51)

Education (years)

 ≤9

6615 (35.5)

19,898 (40.3)

1.0 (ref)

1.0 (ref)

1.0 (ref)

 9–12

6911 (37.1)

18,788 (38)

1.10 (1.06–1.15)

1.10 (1.06–1.15)

1.09 (1.04–1.14)

 ≥13

4785 (25.7)

9968 (20.2)

1.44 (1.38–1.51)

1.44 (1.38–1.51)

1.37 (1.30–1.45)

 Missing

327 (1.8)

764 (1.6)

1.29 (1.13–1.47)

1.28 (1.13–1.47)

1.20 (1.00–1.43)

Occupation

 Not working (retired/unemployed)

13,765 (73.9)

38,873 (78.7)

1.0 (ref)

1.0 (ref)

1.0 (ref)

 Higher clerk/ leading position

850 (4.6)

1357 (2.8)

1.77 (1.62–1.93)

1.97 (1.80–2.17)

1.41 (1.27–1.58)

 Qualified white collar

1072 (5.8)

2077 (4.2)

1.46 (1.35–1.57)

1.60 (1.48–1.74)

1.20 (1.09–1.32)

 Other white collar

430 (2.3)

959 (1.9)

1.27 (1.13–1.42)

1.39 (1.24–1.57)

1.06 (0.92–1.26)

 Self-employed excl. Farmers

648 (3.5)

1548 (3.1

1.18 (1.08–1.30)

1.28 (1.16–1.42)

1.16 (1.04–1.30)

 Farmer

201 (1.1)

550 (1.1)

1.03 (0.88–1.21)

1.12 (0.95–1.32)

1.03 (0.86–1.24)

 Foreman/technician

37 (0.2)

60 (0.1)

1.74 (1.16–2.62)

1.96 (1.30–2.96)

1.74 (1.10–2.75)

 Skilled within trade, service or care

494 (2.7)

1289 (2.6)

1.08 (0.97–1.20)

1.18 (1.06–1.32)

0.97 (0.85–1.10)

 Skilled blue collar worker

360 (1.9)

900 (1.8)

1.13 (1.00–1.28)

1.29 (1.13–1.47)

1.04 (0.90–1.21)

 Other blue collar worker

635 (3.4)

1566 (3.2)

1.15 (1.04–1.26)

1.29 (1.17–1.43)

1.08 (0.96–1.21)

 Missing

146 (0.8)

239 (0.5)

1.72 (1.40–2.12)

1.87 (1.52–2.30)

1.62 (1.04–2.51)

Income (SEK) c

 Mean (1000s) ± SD

232 ± 505

209 ± 296

   

 Quartile 1

4275 (22.9)

12,557 (25.4)

1.0 (ref)

1.0 (ref)

1.0 (ref)

 Quartile 2

4411 (23.7)

12,806 (25.9)

1.01 (0.96–1.06)

1.02 (0.97–1.07)

1.00 (0.95–1.06)

 Quartile 3

4490 (24.1)

12,499 (25.3)

1.06 (1.01–1.11)

1.09 (1.04–1.15)

1.02 (0.96–1.08)

 Quartile 4

5462 (29.3)

11,556 (23.4)

1.39 (1.32–1.46)

1.46 (1.38–1.53)

1.23 (1.16–1.31)

Immigrant status

 Swedish background

16,503 (88.5)

43,930 (88.9)

1.0 (ref)

–

–

 Foreign background

2135 (11.5)

5488 (11.1)

1.04 (0.98–1.09)

–

–

  1. Data are n (%) unless otherwise specified
  2. aAdjusted for sex, age, region, educational level, type of employment, disposable income, number of years since first AF diagnosis, calendar year of inclusion in the study, previous hospitalization for bleeding, anaemia, myocardial infarction, heart failure, valvular disease (other than the exclusion criteria), pacemaker or ICD, diabetes, chronic kidney disease, chronic obstructive pulmonary disease, alcohol index, dementia, hospitalization for falls occurring more than once and use of the following drugs < 6 months before the index date: beta blockers, digoxin, class 1 antiarrhthmic drugs and sotalol
  3. bUrban = Stockholm, Malmö and Göteborg; South = Götaland; Mid = Svealand; North = Norrland
  4. cQuartile 1 = < 130,000 SEK; Quartile 2 = 130,000–165,000 SEK; Quartile 3 = 165,000–238,000 SEK; Quartile 4 = ≥238,000 SEK)
  5. CI confidence interval, NVAF non-valvular atrial fibrillation, OR odds ratio, SD standard deviation, SEK Swedish Krona
Back to article page

BMC Cardiovascular Disorders

ISSN: 1471-2261

Contact us