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Table 2 Characteristics of 12,159 incident atrial fibrillation patients by medication adherence status

From: Risk factors for medication non-adherence among atrial fibrillation patients

  Adherent
n = 11,388
(93.7%)
Not Adherent
n = 771
(6.3%)
P
Socio-demographics
Age, years    < 0.001
 Median 72.7 70.1  
 25th – 75th % 64.4–79.9 59.5–79.1  
Age group, years, n (%)    < 0.001
  < 65 3017 (26.5) 293 (38.0)  
 65–74 3549 (31.2) 198 (25.7)  
 75–84 3523 (30.9) 185 (24.0)  
  ≥ 85 1299 (11.4) 95 (12.3)  
Male, n (%) 6498 (57.1) 435 (56.4) 0.735
Race/Ethnicity, n (%)    < 0.001
 Non-Hispanic White 8505 (74.7) 502 (65.1)  
 Non-Hispanic Black 572 (5.0) 81 (10.5)  
 Non-Hispanic Asian/Pacific Islander 775 (6.8) 64 (8.3)  
 Hispanic 889 (7.8) 75 (9.7)  
 Other/Unknown 647 (5.7) 49 (6.4)  
Marital Status, n (%)    0.006
 Married/Partner 7470 (65.6) 463 (60.1)  
 Not Married/Partner 3788 (33.3) 300 (38.9)  
 Unknown 130 (1.1) 8 (1.0)  
Educational Attainment, n (%)    0.299
 Less than High School 929 (8.2) 72 (9.3)  
 High School Graduate 2110 (18.5) 145 (18.8)  
 Some College 4075 (35.8) 290 (37.6)  
 Bachelor’s Degree or Higher 3999 (35.1) 243 (31.5)  
 Unknown 275 (2.4) 21 (2.7)  
Household Income, n (%)    0.008
 $25,000 or less 1694 (14.9) 150 (19.5)  
 $25,001 – 50,000 2477 (21.8) 168 (21.8)  
 $50,001 – 80,000 1967 (17.3) 122 (15.8)  
 More than $80,000 2501 (22.0) 169 (21.9)  
 Unknown 2749 (24.1) 162 (21.0)  
Questionnaire Language, n (%)    0.349
 English 11,077 (97.3) 752 (97.5)  
 Spanish 280 (2.5) 19 (2.5)  
 Mandarin 31 (0.3) 0 (0.0)  
Region, n (%)    0.941
 Northern California 5854 (51.4) 395 (51.2)  
 Southern California 5534 (48.6) 376 (48.8)  
Health Behaviors
Physical Activity (past month), n (%)    < 0.001
 None 854 (7.5) 86 (11.2)  
 Low/Moderate 7683 (67.5) 532 (69.0)  
 High 2802 (24.6) 149 (19.3)  
 Unknown 49 (0.4) 4 (0.5)  
Cigarette Use (past year), n (%)    0.002
 Never 4758 (41.8) 303 (39.3)  
 Former 5759 (50.6) 383 (49.7)  
 Current 624 (5.5) 67 (8.7)  
 Unknown 247 (2.2) 18 (2.3)  
Alcohol Use (past year), n (%)    < 0.001
 Never 2364 (20.8) 105 (13.6)  
 Former 2245 (19.7) 169 (21.9)  
 Current 6585 (57.8) 484 (62.8)  
 Unknown 194 (1.7) 13 (1.7)  
Self-Reported Health Status
Poor Physical Health (past month), n (%)    < 0.001
 0 days 6313 (55.4) 320 (41.5)  
 1–7 days 2156 (18.9) 196 (25.4)  
 8–21 days 816 (7.2) 78 (10.1)  
 22–28 days 80 (0.7) 7 (0.9)  
  ≥ 29 days 821 (7.2) 74 (9.6)  
 Unknown 1202 (10.6) 96 (12.5)  
Poor Mental Health (past month), n (%)    < 0.001
 0 days 7835 (68.8) 400 (51.9)  
 1–7 days 1401 (12.3) 134 (17.4)  
 8–21 days 593 (5.2) 66 (8.6)  
 22–28 days 66 (0.6) 6 (0.8)  
  ≥ 29 days 422 (3.7) 50 (6.5)  
 Unknown 1071 (9.4) 115 (14.9)  
Self-Rated Current Health, n (%)    < 0.001
 Poor 641 (5.6) 59 (7.7)  
 Fair 2581 (22.7) 228 (29.6)  
 Good 4561 (40.1) 271 (35.2)  
 Very Good 2890 (25.4) 168 (21.8)  
 Excellent 625 (5.5) 36 (4.7)  
 Unknown 90 (0.8) 9 (1.2)  
Sleep Affecting Daily Function (average), n (%)    < 0.001
 Never 2747 (24.1) 145 (18.8)  
 Rarely 5283 (46.4) 294 (38.1)  
 1–3 days/week 1685 (14.8) 154 (20.0)  
 4–6 days/week 431 (3.8) 44 (5.7)  
 Almost every day 1060 (9.3) 126 (16.3)  
 Unknown 182 (1.6) 8 (1.0)  
Memory Decline (past 2–3 years), n (%)    < 0.001
 No 5582 (49.0) 294 (38.1)  
 Yes 4601 (40.4) 397 (51.5)  
 Unknown 1205 (10.6) 80 (10.4)  
Health Literacy, n (%)    < 0.001
 Adequate 8813 (77.4) 536 (69.5)  
 Inadequate 2575 (22.6) 235 (30.5)  
Medical History
Low-Dose Aspirin (past year; ≤100 mg/tablet), n (%)    0.043
 Did not use in the last 12 mo. 6462 (56.7) 404 (52.4)  
 Did use in the last 12 mo. 4488 (39.4) 339 (44.0)  
 Unknown 438 (3.9) 28 (3.6)  
Aspirin or Aspirin-Product (past year; ≥325 mg/tablet), n (%)    0.240
 Did not use in the last 12 mo. 8431 (74.0) 551 (71.5)  
 Did use in the last 12 mo. 2287 (20.1) 174 (22.6)  
 Unknown 670 (5.9) 46 (6.0)  
Body Mass Index (kg/m2), n (%)    0.003
  < 25 3211 (28.2) 191 (24.8)  
 25–30 3915 (34.4) 254 (32.9)  
  ≥ 30 3492 (30.7) 284 (36.8)  
 Unknown 770 (6.8) 42 (5.5)  
Charlson Comorbidity Index (past year), n (%)    0.124
 0 3773 (33.1) 255 (33.1)  
 1 2346 (20.6) 175 (22.7)  
 2 1652 (14.5) 124 (16.1)  
  ≥ 3 3617 (31.8) 217 (28.2)  
CHADS2 Score (past five years), n (%)    0.049
 0 1849 (16.2) 155 (20.1)  
 1 3959 (34.8) 254 (32.9)  
 2 3782 (33.2) 245 (31.8)  
  ≥ 3 1798 (15.8) 117 (15.2)  
Coronary Heart Disease, n (%) 1372 (12.1) 92 (11.9) 0.955
Chronic Heart Failure, n (%) 2457 (21.6) 167 (21.7) 0.964
Dementia, n (%) 288 (2.5) 19 (2.5) > 0.999
Depression, n (%) 2309 (20.3) 191 (24.8) 0.004
Diabetes Mellitus, n (%) 3096 (27.2) 236 (30.6) 0.041
Hypertension, n (%) 8961 (78.7) 568 (73.7) 0.001
Ischemic Stroke or Transient Ischemic Attack, n (%) 604 (5.3) 39 (5.1) 0.868
  1. p-values based on chi-square, Fisher’s exact and Wilcoxon signed-rank tests