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Table 2 Change in coronary plaque composition over serial CCTA

From: Progression of coronary atherosclerotic plaque burden and relationship with adverse cardiovascular event in asymptomatic diabetic patients

Patients (n = 197)

Patients with CACS ≤10

Patients with CACS > 10

P value

Baseline

Repeat

Δ-Value

Baseline

Repeat

Δ-Value

Total lumen vol.

125.5 (±113.7)

125.48 (±107.0)

2.95 (±67.8)

182.3 (±131.8)

194.0 (±141.8)

10.8 (±110.3)

0.060

Total plaque vol.

85.8 (±89.4)

104.4 (±106.5)

20.6 (±63.5)

102.1 (±83.4)

132.1 (±116.5)

30.1 (±102.6)

0.002

PAV, % (±SD)

39.3 (±16.4)

44.0 (±16.4)

5.7 (±13.9)

34.7 (±12.8)

38.9 (±12.7)

4.2 (±13.6)

0.676

Total dense calcium

 Mean (±SD)

6.7 (±18.9)

6.8 (±16.4)

0.3 (±13.6)

23.1 (±28.0)

28.8 (±35.9)

5.7 (±28.5)

0.002

 Median [IQR]

0 [0, 5.2]

0 [0,8.2]

0 [0,2.5]

12.2 [6.5,28.0]

17.2 [7.6,31.1]

1.43 [−0.81,4.11]

0.387

 PAV, % (±SD)

2.5 (±4.5)

3.0 (±5.2)

0.6 (±2.5)

8.0 (±7.5)

9.1 (±8.8)

1.1 (±4.4)

0.360

Total fibrotic vol.

 Mean (±SD)

63.5 (±61.9)

71.1 (±63.0)

9.2 (±40.6)

65.1 (±49.5)

77.8 (±62.9)

12.6 (±53.3)

0.029

 PAV, % (±SD)

30.9 (±14.2)

31.7 (±13.0)

0.9 (±12.9)

22.9 (±10.5)

23.7 (±11.3)

0.7 (±10.7)

0.70

Total low attenuation vol.

 Mean (±SD)

15.9 (±25.9)

29.7 (±49.6)

14.3(±34.9)

14.6 (±20.9)

25.5 (±35.0)

10.9 (±34.1)

0.018

 PAV, % (±SD)

6.7 (±7.9)

10.2 (±10.0)

3.6 (±7.9)

4.3 (±4.7)

6.2 (±6.6)

1.8 (±7.4)

0.850

  1. Continuous variables are presented as mean (±SD) and median [IQR] for the dense calcium volume. Percent Atheroma Volume (PAV) is presented as percentages. Volumes (Vol.) are measured in mm3. Differences between delta (Δ) values were tested with a student’s t-test (p) in normal distributed variables and in non-normal distributed variables with the non-parametric Kruskal-Wallis test (p*)