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Table 3 Association between serum IL8 levels and risk of all cause, CVD and cancer related mortality expressed as hazard ratios (HR), 95% confidence intervals (CI)

From: Serum IL8 is not associated with cardiovascular events but with all-cause mortality

 

IL8Q1

IL8Q2

p

IL8Q3

p

IL8Q4

p

All-cause mortality (n = 647)

869/127

849/153

 

843/178

 

803/189

 

 Crude (n = 4011)

1

1.21 (0.95–1.53)

0.11

1.40 (1.11–1.76)

0.004

1.54 (1.23–1.93)

< 0.0001

 Model 1a (n = 3845)

1

1.13 (0.89–1.45)

0.30

1.34 (1.06–1.70)

0.01

1.35 (1.07–1.71)

0.01

 Model 1b (n = 3837)

1

1.09 (0.85–1.39)

0.38

1.27 (1.01–1.62)

0.04

1.28 (1.02–1.63)

0.03

CVD related mortality (n = 136)

885/24

881/38

 

878/32

 

868/42

 

 Crude (n = 3648)

1

1.58 (0.95–2.64)

0.07

1.35 (0.79–2.29)

0.26

1.80 (1.01–2.97)

0.02

 Model 1a (n = 3509)

1

1.48 (0.80–2.32)

0.15

1.35 (0.77–2.36)

0.28

1.48 (0.87–2.53)

0.14

 Model 1b (n = 3504)

1

1.37 (0.79–2.38)

0.25

1.24 (0.71–2.17)

0.44

1.35 (0.79–2.32)

0.26

Cancer related mortality (n = 266)

906/55

903/68

 

934/64

 

887/79

 

 Crude (n = 3896)

1

1.23 (0.89–1.78)

0.18

1.15 (0.80–1.65)

0.44

1.46 (1.04–2.07)

0.03

 Model 1a (n = 3732)

1

1.18 (0.82–1.71)

0.36

1.09 (0.75–1.59)

0.62

1.27 (0.89–1.82)

0.18

 Model 1b (n = 3724)

1

1.15 (0.79–1.66)

0.45

1.06 (0.73–1.53)

0.75

1.23 (0.86–1.77)

0.24

  1. Numbers of study participants is reported for the crude model. Missing values in the confounders are specified in Table 1. Model 1a: adjusted by sex, smoking, alcohol consumption, physical activity at work and during leisure time; Model 1b: model 1a + systolic and diastolic blood pressure, central obesity, cholesterol and glucose levels