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Table 4 Characteristics and Strain Parameters of CS Patients With Normal LV and RV Function and Control Patients Without CSa

From: Diagnostic and predictive value of speckle tracking echocardiography in cardiac sarcoidosis

Variable

CS Patients with LVEF > 52% (men) and > 54% (women) (n = 23)

Control Patients (N = 97)

P Value

Age, y

52.9 ± 10.0

40.4 ± 13.6

.0001

Female sex, No. (%)

5 (21.7)

61 (62.9)

.0001

BMI, kg/m2

29.9 ± 4.7

25.9 ± 4.8

.001

Systolic BP, mm Hg

123.3 ± 16.5

115.6 ± 15.5

.05

Diastolic BP, mm Hg

71.6 ± 7.2

71.2 ± 9.8

.81

Heart rate, bpm

75.3 ± 20.4

72.7 ± 13.3

.45

LV mass indexed for BSA, g/m2

92.7 ± 22.9

76.7 ± 13.6

.0001

LVEF, %

57.3 ± 3.8

63.9 ± 3.8

.0001

E/A

1.1 ± 0.6

1.6 ± 0.6

.001

E/e′

9.2 ± 4.4

7.7 ± 1.9

.01

LV GLS, %

−15.9 ± 2.5

−18.2 ± 2.7

.001

LV GCS, %

−22.5 ± 4.7

−21.9 ± 4.7

.60

LV GRS, %

37.1 ± 13.1

44.1 ± 12.1

.02

LV GLSR, s−1

−1.0 ± 1.2

−1.0 ± 0.2

.27

LV GCSR, s−1

−1.5 ± 0.4

− 1.4 ± 0.3

.22

LV GRSR, s−1

2.0 ± 0.4

2.2 ± 0.6

.09

LV GLSRe, s−1

0.9 ± 0.2

1.1 ± 0.2

.004

LV GCSRe, s−1

1.6 ± 0.6

1.4 ± 0.3

.08

LV GRSRe, s−1

−1.4 ± 1.3

−2.1 ± 0.8

.002

RV GLS, %

−16.9 ± 4.5

−24.1 ± 4.0

.0001

RV GLSR, s−1

− 1.1 ± 0.3

−1.4 ± 0.3

.0001

RV GLSRe, s−1

1.0 ± 0.3

1.5 ± 0.4

.0001

RV free wall GLS, %

−19.1 ± 5.1

−26.0 ± 5.2

.0001

RV free wall GLSR, s−1

− 1.3 ± 0.4

−1.6 ± 0.4

.003

RV free wall GLSRe, s−1

1.1 ± 0.4

1.9 ± 0.8

.0001

  1. Abbreviations: BMI body mass index; BP blood pressure; bpm beats per minute; BSA body surface area; CS cardiac sarcoidosis; E/A ratio of early (E) to late (A) ventricular filling velocity; E/e′, ratio between early mitral inflow velocity and mitral annular early diastolic velocity; GCS global circumferential strain; GCSR global circumferential strain rate; GCSRe early diastolic circumferential strain rate; GLS global longitudinal strain; GLSR global longitudinal strain rate; GLSRe early diastolic longitudinal strain rate; GRS global radial strain; GRSR global radial strain rate; GRSRe early diastolic global radial strain rate; LV left ventricular; LVEF left ventricular ejection fraction; RV right ventricular
  2. a Mean ± SD unless otherwise indicated