Associations between circulating resistin concentrations and left ventricular mass are not accounted for by effects on aortic stiffness or renal dysfunction

Table 3 Impact of adjustments for estimated glomerular filtration rate (eGFR), aortic pulse wave velocity (PWV) or C-reactive protein (CRP) on the relative contribution of circulating resistin concentrations to variations in left ventricular mass index (LVMI) in a community sample (n = 647)

Models with→	^a		^a + eGFR		^a + PWV		^a + CRP
Models with→	β-coeff ±SEM	p value	β-coeff±SEM	p value	β-coeff±SEM	p value	β-coeff±SEM	p value
Age	0.156 ± 0.048	=0.0012	0.097 ± 0.056	=0.09	0.111 ± 0.052	=0.028	0.155 ± 0.049	=0.0015
Male gender	0.030 ± 0.040	=0.45	0.032 ± 0.040	=0.42	0.032 ± 0.040	=0.43	0.029 ± 0.041	=0.47
Weight	0.147 ± 0.039	=0.0002	0.148 ± 0.039	=0.0002	0.153 ± 0.039	=0.0001	0.150 ± 0.041	=0.0002
SBP	0.218 ± 0.041	< 0.0001	0.211 ± 0.041	< 0.0001	0.191 ± 0.043	< 0.0001	0.212 ± 0.041	< 0.0001
Log resistin	0.090 ± 0.036	=0.014	0.075 ± 0.036	=0.044	0.084 ± 0.036	=0.022	0.087 ± 0.036	=0.017
eGFR or PWV or CRP	–	–	−0.098 ± 0.051	=0.052	0.102 ± 0.048	=0.047	0.004 ± 0.043	=0.92
HOMA-IR	0.094 ± 0.037	=0.012	0.082 ± 0.038	=0.032	0.090 ± 0.037	=0.017	0.096 ± 0.037	=0.011

β-coeff standardized β-coefficient, BMI body mass index, SBP office systolic blood pressure, HOMA-IR homeostasis model of insulin resistance. ^aAdditional factors included in the stepwise regression models include regular smoking, regular alcohol intake, treatment for hypertension and diabetes mellitus or an HbA1c > 6.5%

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