Associations between circulating resistin concentrations and left ventricular mass are not accounted for by effects on aortic stiffness or renal dysfunction

Table 2 Impact of adjustments for estimated glomerular filtration rate (eGFR), pulse wave velocity (PWV) or C-reactive protein (CRP) on the relative contribution of circulating resistin concentrations to variations in inappropriate left ventricular mass (LVM_inappr) in a community sample (n = 647)

Models with→	^a		^a + eGFR		^a + PWV		^a + CRP
Models with→	β-coeff ±SEM	p value	β-coeff±SEM	p value	β-coeff±SEM	p value	β-coeff±SEM	p value
Age	−0.022 ± 0.051	=0.67	−0.118 ± 0.060	=0.048	−0.022 ± 0.055	=0.69	−0.034 ± 0.051	=0.50
Male gender	0.091 ± 0.045	=0.037	0.090 ± 0.044	=0.043	0.091 ± 0.044	=0.047	0.091 ± 0.045	=0.042
BMI	0.244 ± 0.046	< 0.0001	0.227 ± 0.046	< 0.0001	0.257 ± 0.049	< 0.0001	0.216 ± 0.049	< 0.0001
SBP	−0.088 ± 0.043	=0.0075	−0.133 ± 0.043	=0.0022	−0.089 ± 0.046	=0.0076	−0.122 ± 0.043	=0.0050
Log resistin	0.119 ± 0.038	=0.0018	0.130 ± 0.038	=0.0006	0.118 ± 0.038	=0.0020	0.149 ± 0.038	=0.0001
eGFR or PWV or CRP	–	–	−0.143 ± 0.053	=0.0069	0.002 ± 0.050	=0.98	0.012 ± 0.045	=0.78
HOMA-IR	0.114 ± 0.039	0.0035	0.098 ± 0.039	=0.012	0.083 ± 0.037	=0.0027	0.121 ± 0.039	=0.0019

β-coeff standardized β-coefficient, BMI body mass index, SBP office systolic blood pressure; HOMA-IR homeostasis model of insulin resistance. ^aAdditional factors included in the stepwise regression models include regular smoking, regular alcohol intake, treatment for hypertension and diabetes mellitus or an HbA1c > 6.5%

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