Skip to main content

Table 2 Genotype and allele distributions in Atrial fibrillation patients and controls

From: Association between chymase gene polymorphisms and atrial fibrillation in Chinese Han population

Variant

Allele

Group

n

Genotype (frequency)

p

OR (95% CI), p

Allele (frequency)

OR (95%CI), p

Hardy-Weinberg equilibrium

1/2

1/1

1/2

2/2

1/1 + 1/2vs 2/2

1

2

1 vs 2

χ2

p

rs1956921

C/T

AF

126

2 (1.59%)

25 (19.84%)

99 (78.57%)

0.285

0.629 (0.353–1.212) 0.114

29 (11.51%)

223 (88.49%)

0.664 (0.396–1.113) 0.118

0.084

0.7719

controls

119

3 (2.52%)

33 (27.73%)

83 (69.75%)

39 (16.39%)

199 (83.61%)

0.017

0.8960

rs1800875

A/G

AF

124

10 (8.06%)

38 (30.65%)

76 (81.29%)

0.009

0.500 (0.300–0.832) 0.007

58 (23.39%)

190 (76.61%)

0.685 (0.458–1.023) 0.064

2.601

0.1068

controls

120

7 (5.83%)

60 (50.00%)

53 (44.17%)

74 (30.83%)

166 (69.17%)

3.561

0.0592

rs1800876

T/C

AF

119

23 (19.33%)

59 (49.58%)

37 (31.09%)

0.082

1.122 (0.652–1.932) 0.678

105 (44.12%)

133 (55.88%)

1.298 (0.900–1.872) 0.162

5.502

0.0190

controls

119

11 (9.24%)

68 (57.14%)

40 (33.62%)

90 (37.82%)

148 (62.18%)

0.036

0.9520

sc5244

C/T

AF

126

11 (8.73%)

44 (34.92%)

71 (56.35%)

0.225

0.859 (0.518–1.426) 0.557

66 (26.19%)

186 (73.81%)

1.017 (0.677–1.527) 0.934

1.180

0.2774

controls

116

5 (4.31%)

50 (43.10%)

61 (52.59%)

60 (25.86%)

172 (74.14%)

1.785

0.1816

rs1885108

A/G

AF

126

16 (12.70%)

60 (47.62%)

50 (39.68%)

0.471

0.732 (0.434–1.234) 0.241

92 (36.51%)

160 (63.49%)

0.805 (0.560–1.157) 0.241

0.093

0.7603

controls

120

19 (15.83%)

62 (51.67%)

39 (32.50%)

100 (41.67%)

140 (58.33%)

0.474

0.4911

  1. CI Confidence interval, OR Odds ratio. The minor allele was referred to as allele 1 and the major allele as allele 2. OR estimated by two-tailed P values and 95% confidence intervals (95% CI)