Table 1 Study characteristics
Study, Year | Study size (POTS, Healthy) | Mean Aged (POTS, Healthy) | Matched case-control or not? | Duration of HR/HRV parameter measurement (Angle of tilt) | Orthostasis induction method | Country of study | Outcome Recorded |
|---|---|---|---|---|---|---|---|
Jacob 2019 [22] | 12,10 | 30 ± 1.8, 32 ± 3 | Unmatched | 30 Minutes (750) | HUTT | Israel | HF, HR |
Owens 2018 [23] | 20,20 | 36 ± 10.84, 35 ± 7.56 | Unmatched | 10 Minutes (600) | HUTT | UK | HF, LF |
Goff 2017 [24] | 9,20 | NA, NA | Unmatched | 24 Hours | Daily life activity | Australia | rMSSD |
Moon 2016 [25] | 46,67 | 28.9 ± 1.9, 49.4 ± 2.1 | Unmatched | 20 Minutes | Active standing | Korea Republic | HR |
Freitas 2015 [26] | 10,12 | 29.4 ± 8.5, 33.8 ± 5.9 | Matched | 40 min (700) | HUTT | Portugal | HR, HF |
Yoshida 2014 [27] | 70,38 | 13.7 ± 0.1, 13.5 ± 0.1 | Unmatched | 7 min (900) | Active standing | Japan | HR, LF/HF-Ratio |
Medow 2014 [28] | 12,19 | Median: 20.8, 21.4 | Unmatched | 10 Minutes (700) | HUTT | USA | HR, LF(n.u), LF(n.u) |
Mallien 2014 [29] | 38,31 | 25.3 ± 7, 26.2 ± 6.3 | Matched | Overnight | HUTT | Germany | HR, LF, HF, LF/HF-Ratio |
Plash 2013 [30] | 15,15 | 36 ± 3, 33 ± 2 | Unmatched | 30 Minutes | Active standing | USA | HR |
Ocon 2012 [31] | 16,20 | 21 ± 1, 23 ± 1 |  | 10 Minutes (750) | HUTT | USA | HR |
Brewster 2012 [32] | 54,26 | 35 ± 2, 27 ± 1 | Unmatched | 5 Minutes | Active standing | USA | HR |
Galbreath 2011 [33] | 17,17 | 27 ± 9, 31 ± 10 | Unmatched | 5 Minutes (600) | HUTT | USA | HR, HF, LF, rMSSD, RR-Interval, HF (n.u), LF (n.u) |
Baumert 2011 [34] | 13,12 | (32 ± 13, 23 ± 2), | Unmatched | 10 Minutes (400) | HUTT | Australia | HR |
Fu 2010 [35] | 27,16 | 26 (21–33), 28 (23,35) | Unmatched | 45 Minutes (60%) *grip | HUTT | USA | HR |
Ocon 2009 [13] | 9,7 | NA, NA | Unmatched | 10 Minutes (700) | HUTT | USA | RR-Interval, LF, HF, LF/HF-Ratio, LF(n.u), HF(n.u), HR |
Garland 2007 [36] | 150,63 | 34.5 ± 10.7, 30.2 ± 9.3 | Unmatched | 5 Minutes | Active standing | USA | HR |
Stewart 2006 [37] | 20,10 | 17 ± 2, 17 ± 1 | Matched | 10 Minutes (700) | HUTT | USA | HR, LF/HR-Ratio, HF, LF |
Meier 2006 [38] | 21,39 | 15.5 ± 2.2, 11.7 ± 2.7 | Unmatched | 12 Minutes (600) | HUTT | The Netherlands | HR |
Garland 2005 [39] | 136,191 | 29.1 ± 8.0, 32.2 ± 9.9 | Unmatched | 30 Minutes (600) | HUTT | USA | HR |
Stewart 2000 [40] | 22,10 | Median: 15.2, 15.8 | Unmatched | 30 Minutes (700) | HUTT | USA | HR, HF(n.u), LF(n.u), LF/HF-Ratio, HF, LF, rMSSD, RR-Interval |