Fig. 4
From: Heat shock protein 90 is downregulated in calcific aortic valve disease
The molecular network of differentially expressed proteins in CAVD generated by Ingenuity Pathway Analysis. The Ingenuity Pathway Analysis (IPA) Core Analysis-based network displays interactions between proteins that were differentially expressed in stenotic valves as compared to control valves. Up- and down-regulated proteins are in red and green, respectively. Molecules not marked with a color were not altered in the data set but they are possible connections suggested by IPA. Molecules are represented with various shapes that represent the functional class of the gene product. A solid line represents direct interactions and a dashed line represents an indirect interaction. The full names of the molecules are given in Table 3