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Table 1 Baseline characteristics

From: Bisoprolol transdermal patch for perioperative care of non-cardiac surgery in patients with hypertrophic obstructive cardiomyopathy

 

Switching therapy group

Add-on therapy group

n = 6

n = 4

Age (years)

72 ± 13

68 ± 14

Sex (male:female)

3 (50):3 (50)

0 (0):4 (100)

Type of surgerya

 Intraperitoneal

2

1

 Orthopedic

2

1

 Peripheral Vascular

1

 Lung

1

 Urological

1

 Thyroid

1

Surgical riskb

 High

1 (17)

1 (25)

 Intermediate

5 (83)

1 (25)

 Low

0 (0)

2 (50)

Oral β-blocker

 Bisoprolol (7.5 mg)

1 (17)

 Bisoprolol (5 mg)

5 (83)

 None

4 (100)

Bisoprolol transdermal patch

 8 mg

6 (100)

1 (25)

 4 mg

0 (0)

3 (75)

 Class IA agentsc

5 (83)

4 (100)

 Class III agents

0 (0)

0 (0)

 Calcium-channel blockers

5 (83)

1 (25)

 Diuretics

1 (17)

0 (0)

 Height (cm)

156 ± 11

155 ± 5

 Weight (kg)

59 ± 15

57 ± 10

 BMI (kg/m2)

24 ± 4

24 ± 3

NYHA class

 I

2 (33)

1 (25)

 IIs

2 (33)

3 (75)

 IIm

1 (17)

0 (0)

 III

1 (17)

0 (0)

 IV

0 (0)

0 (0)

Type of obstruction

 LVOTO

5 (83)

3 (75)

 MVO

1 (17)

1 (25)

 Prior PTSMA

4 (67)

0 (0)

 FH-SCD

1 (17)

0 (0)

 VT/Vf

0 (0)

0 (0)

 Af

3 (50)

0 (1)

 Prior pacemaker/ICD

1 (17)

0 (2)

Measurements of the left ventricle

 IVST (mm)

15 ± 1

15 ± 5

 PWT (mm)

12 ± 2

12 ± 2

 LAD (mm)

42 ± 8

37 ± 2

 LVDd (mm)

44 ± 8

40 ± 2

 LVDs (mm)

28 ± 9

22 ± 1

  1. BMI body mass index, NYHA New York Heart Association, LVOT left ventricular outflow obstruction, MVO mid-ventricular obstruction, PTSMA percutaneous transluminal septal myocardial ablation, FH family history, SCD sudden cardiac death, VT/Vf ventricular tachycardia/ventricular fibrillation, Af atrial fibrillation, ICD implanted cardioverter defibrillator, IVST interventricular septal thickness, PWT posterior wall thickness, LAD left atrial diameter, LVDd left ventricular end-diastolic diameter, LVDs left ventricular end-systolic diameter, EF ejection fraction
  2. aThe type of surgery is presented as per the European Society of Cardiology and the European Society of Anaesthesiology guideline [13].
  3. bThe surgical risk estimate was a broad approximation of the 30-day risk of cardiovascular death and myocardial infarction that considers only the specific surgical intervention, without considering the patient’s comorbidities [12].
  4. cCibenzoline (100–300 mg)