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Table 2 Diagnostic performance of miR-1, cTnI and combination in patients with early AMI

From: Circulating microRNA-1 in the diagnosis and predicting prognosis of patients with chest pain: a prospective cohort study

Biomarker

AUC (95%CI)

P value

Sen.

Spe.

PPV

NPV

LR+

LR-

miR-1

0.863 (0.820~0.906)

0.000

87.9

80.2

0.823

0.865

4.450

0.150

cTnI

0.864 (0.823~0.906)

0.000

79.3

91.6

0.908

0.810

9.461

0.226

miR-1 + cTnI

0.931 (0.904~0.959)

0.000

86.2

90.4

0.799

0.947

3.816

0.005

  1. miR-1microRNA-1, cTnI Cardiac troponin I, AUC the area under the receiver operating characteristics curve, Cl confidence interval, Sen. sensitivity (%), Spe. specificity (%), PPV positive predictive value, NPV negative predictive value, LR+ positive likelihood ratio, LR- negative likelihood ratio; Italics mean that joint diagnosis is calculated by parallel test method
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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