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Table 2 Predictors of HCM-related death and overall MACEs

From: Modes of death and clinical outcomes in adult patients with hypertrophic cardiomyopathy in Thailand

Variables HCM-Related Death MACEs
Univariate Analysis Univariate Analysis Multivariate Analysis
Hazard Ratio p Value Hazard Ratio p Value Hazard Ratio p Value
Age ≥ 65 years 0.78 0.66 2.01 0.01* 1.66 0.09
Female 1.24 0.65 2.33 < 0.01* 1.66 0.11
BSA ≤ 1.5 m2 2.03 0.11 1.97 0.01* 1.70 0.08
NYHA III-IV 1.36 0.58 3.00 < 0.01* 1.27 0.55
Heart rate > 90/min 2.56 0.07 3.05 < 0.01* 2.18 0.04**
Family History of SCD 0.88 0.73 1.03 0.94   
AF on ECG 1.83 0.28 2.05 0.05 2.81 0.01**
Heart failure at presentation 1.32 0.59 3.44 < 0.01* 2.93 < 0.01**
Maximal septal thickness ≥ 25 mm 1.15 0.80 0.97 0.94   
LVEF < 60% 0.60 0.36 1.75 0.12   
Septal reductive therapy 0.58 0.59 1.12 0.65   
  1. AF atrial fibrillation, BSA body surface area, ECG electrocardiography, LVEF left ventricular ejection fraction; MR mitral regurgitation, NYHA New York Heart Association, SCD sudden cardiac death