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Table 1 Baseline characteristics of study patients

From: Modes of death and clinical outcomes in adult patients with hypertrophic cardiomyopathy in Thailand

Variables n = 161
Age (year) 66 ± 16
Age stratified by decade (years) [n (%)]
 – < 20
 – 20-29
 – 30-39
 – 40-49
 – 50-59
 – 60-69
 – 70-79
 – 80-89
 – ≥90
0 (0%)
4 (3%)
5 (3%)
19 (12%)
21 (13%)
36 (22%)
41 (25%)
32 (20%)
3 (2%)
Age at presentation (year) 58 ± 17
Female [n (%)] 93 (58%)
Family history of HCM/ SCD [n (%)] 17 (12%)/13 (9%)
History of syncope [n (%)] 8 (5%)
NYHA Class III-IV [n (%)] 21 (13%)
Systolic blood pressure (mmHg) 130 ± 18
Diastolic blood pressure (mmHg) 75 ± 12
Atrial fibrillation at presentation [n (%)] 12 (8%)
- Paroxysmal
- Persistent/permanent
4 (3%)
8 (5%)
LVH on ECG [n (%)] 92 (57%)
Clinical presentation [n (%)]
 Asymptomatic with abnormal murmur 20 (12%)
 Asymptomatic with abnormal EKG 27 (17%)
 Dyspnea on exertion 40 (25%)
 Palpitation 11 (7%)
 Chest pain 33 (21%)
 Syncope 8 (5%)
 Heart failure 15 (9%)
 Stroke 7 (4%)
Functional capacity in Metabolic Equivalents (METS) 7.9 ± 1.7
Hypotensive response to exercise [n (%)] 2 (1%)
Non-sustained ventricular tachycardia [n (%)] 2 (1%)
5-year ESC-SCD risk score 2.1 ± 0.6%
Type [n (%)]
 – Asymmetrical septal hypertrophy
 – Pure apical
 – Apical with mid LV involvement
 – Concentric
 – Localized
 – Pure Mid
81 (50%)
27 (17%)
24 (14%)
26 (16%)
2 (2%)
1 (1%)
Interventricular septal thickness (mm) 18 ± 6
Interventricular septal thickness ≥ 25 mm [n (%)] 24 (15%)
Interventricular septal thickness ≥ 30 mm [n (%)] 9 (5%)
Abnormal papillary muscle [n (%)] 36 (22%)
Resting systolic anterior motion [n (%)] 77 (48%)
 Chordal
 Mild
 Moderate
 Severe
36
23
12
6
Significant LVOT gradient (> 30 mmHg) [n (%)] 38 (24%)
LVEDD (mm) 43 ± 8
LA diameter (mm) 40 ± 9
LAVI (ml/m2) 37 ± 18
LVEF (%) 74 ± 10
Dilated HCM (LVEF< 50%) [n (%)] 6 (4%)
Beta blocker [n (%)] 119 (74%)
Calcium channel blocker [n (%)] 19 (12%)
Amiodarone [n (%)] 14 (9%)
Anticoagulant [n (%)] 40 (25%)
Cardiac implantable electronic device [n (%)]
 – ICD
 – CRT-D
 – Pacemaker
5 (3%)
0 (0%)
8 (5%)
  1. CRT-D implantable cardiac resynchronization therapy defibrillator, ECG electrocardiography, HCM hypertrophic cardiomyopathy, ICD implantable cardioverter defibrillator, LA Left atrium, LAVI left atrial volume index, LVEDD left ventricular end-diastolic diameter, LVEF left ventricular ejection fraction, LVH left ventricular hypertrophy, LVOT left ventricular outflow tract, NYHA New York Heart Association