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Table 2 Longitudinal mean changes and intraclass correlation coefficients (ICC) of KCCQ subscales, MAHFER study

From: Validation of heart failure quality of life tool and usage to predict all-cause mortality in acute heart failure in Uganda: the Mbarara heart failure registry (MAHFER)

HQOL measure Mean (SD) Mean change vs. Baseline (SE) P-value trend ICC (95% CI)
KCCQ
 Physical limitation     0.16 (0.05, 0.41)
  Baseline 12.6 (18.9)  
  Month 1 41.9 (28.9) −29.4 (3.0) <  0.001  
  Month 3 41.2 (25.9) −28.8 (3.5) <  0.001  
 Symptom stability     0.24 (0.08, 0.53)
  Baseline 51.5 (21.1)  
  Month 1 48.5 (20.7) 2.9 (2.9) 0.450  
  Month 3 46.1 (21.7) 5.4 (3.7) 0.142  
 Symptom frequency     0.14 (0.03, 0.45)
  Baseline 38.4 (22.9)  
  Month 1 47.3 (30.9) −9.1 (3.5) 0.046  
  Month 3 52.9 (32.0) −14.5 (4.2) 0.003  
 Symptom burden     0.08 (0.01, 0.56)
  Baseline 40.6 (24.7)  
  Month 1 42.7 (33.3) −8.7 (3.8) 0.046  
  Month 3 52.4 (35.3) −18.5 (4.7) 0.001  
 Total symptom score     0.11 (0.02, 0.48)
  Baseline 39.5 (23.8)  
  Month 1 45.0 (31.9) −8.8 (3.6) 0.046  
  Month 3 52.7 (33.4) −16.5 (4.4) 0.002  
 Self-efficacy     0.45 (0.29, 0.62)
  Baseline 58.7 (21.7)  
  Month 1 31.5 (24.3) 27.2 (3.1) <  0.001  
  Month 3 25.0 (24.4) 33.6 (3.8) <  0.001  
 Quality of life     0.14 (0.03, 0.44)
  Baseline 23.1 (16.1)  
  Month 1 14.5 (22.7) 8.7 (2.5) 0.005  
  Month 3 13.1 (22.2) 10.2 (2.9) 0.024  
 Social limitation     0.13 (0.03, 0.41)
  Baseline 11.9 (18.7)  
  Month 1 13.0 (28.9) −1.2 (3.0) 0.008  
  Month 3 13.8 (26.9) −2.0 (3.5) 0.905  
 Overall summary score     0.13 (0.03, 0.43)
  Baseline 21.8 (15.8)  
  Month 1 28.6 (23.4) −7.7 (2.5) 0.008  
  Month 3 30.2 (21.4) −9.3 (2.9) 0.002  
 Clinical summary score     0.16 (0.04, 0.44)
  Baseline 26.0 (18.6)  
  Month 1 43.4 (25.3) −19.2 (2.8) <  0.001  
  Month 3 46.9 (24.9) −22.6 (3.4) <  0.001  
  1. HQOL Health related quality of life, KCCQ Kansas City Cardiomyopathy Questionnaire, SD Standard deviation, SE Standard Error, ICC Intraclass Correlation Coefficient
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