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Table 3 Correlation between carotid-femoral pulse wave velocity levels and clinical variables among the 105 hypertensive patients

From: Serum levels of sclerostin as a potential biomarker in central arterial stiffness among hypertensive patients

Variables

Carotid–femoral pulse wave velocity (m/s)

Simple linear regression

Multivariable linear regression

r

p value

Beta

Adjusted R2 change

p value

Female

−0.154

0.116

Diabetes mellitus

0.228

0.019*

Age (years)

0.366

<  0.001*

0.325

0.109

<  0.001*

Height (cm)

− 0.017

0.866

Body weight (kg)

−0.003

0.975

Body mass index (kg/m2)

0.025

0.800

Systolic blood pressure (mmHg)

0.334

0.001*

0.236

0.061

0.004*

Diastolic blood pressure (mmHg)

0.100

0.308

Total cholesterol (mg/dL)

−0.110

0.263

Log-Triglyceride (mg/dL)

−0.001

0.991

HDL-C (mg/dL)

−0.267

0.006*

− 0.193

0.025

0.027*

LDL-C (mg/dL)

− 0.019

0.849

Log-Glucose (mg/dL)

0.001

0.998

Blood urea nitrogen (mg/dL)

0.243

0.013*

Creatinine (mg/dL)

0.369

<  0.001*

eGFR (mL/min)

− 0.335

<  0.001*

Total calcium (mg/dL)

−0.027

0.785

Phosphorus (mg/dL)

−0.101

0.306

iPTH (pg/mL)

0.293

0.003*

0.185

0.032

0.022*

Sclerostin (pmol/L)

0.392

<  0.001*

0.255

0.146

0.003*

Log-Dickkopf-1 (pmol/L)

−0.250

0.142

  1. Data of triglyceride, glucose, and dickkopf-1 showed skewed distribution and therefore were log-transformed before analysis
  2. Analysis of data was done using the simple linear regression analyses or multivariable stepwise linear regression analysis (adapted factors were diabetes mellitus, age, systolic blood pressure, HDL-C, blood urea nitrogen, creatinine, eGFR, iPTH, and sclerostin)
  3. HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, iPTH intact parathyroid hormone
  4. *Values of p < 0.05 were considered statistically significant