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Table 3 Correlation between carotid-femoral pulse wave velocity levels and clinical variables among the 105 hypertensive patients

From: Serum levels of sclerostin as a potential biomarker in central arterial stiffness among hypertensive patients

Variables Carotid–femoral pulse wave velocity (m/s)
Simple linear regression Multivariable linear regression
r p value Beta Adjusted R2 change p value
Female −0.154 0.116
Diabetes mellitus 0.228 0.019*
Age (years) 0.366 <  0.001* 0.325 0.109 <  0.001*
Height (cm) − 0.017 0.866
Body weight (kg) −0.003 0.975
Body mass index (kg/m2) 0.025 0.800
Systolic blood pressure (mmHg) 0.334 0.001* 0.236 0.061 0.004*
Diastolic blood pressure (mmHg) 0.100 0.308
Total cholesterol (mg/dL) −0.110 0.263
Log-Triglyceride (mg/dL) −0.001 0.991
HDL-C (mg/dL) −0.267 0.006* − 0.193 0.025 0.027*
LDL-C (mg/dL) − 0.019 0.849
Log-Glucose (mg/dL) 0.001 0.998
Blood urea nitrogen (mg/dL) 0.243 0.013*
Creatinine (mg/dL) 0.369 <  0.001*
eGFR (mL/min) − 0.335 <  0.001*
Total calcium (mg/dL) −0.027 0.785
Phosphorus (mg/dL) −0.101 0.306
iPTH (pg/mL) 0.293 0.003* 0.185 0.032 0.022*
Sclerostin (pmol/L) 0.392 <  0.001* 0.255 0.146 0.003*
Log-Dickkopf-1 (pmol/L) −0.250 0.142
  1. Data of triglyceride, glucose, and dickkopf-1 showed skewed distribution and therefore were log-transformed before analysis
  2. Analysis of data was done using the simple linear regression analyses or multivariable stepwise linear regression analysis (adapted factors were diabetes mellitus, age, systolic blood pressure, HDL-C, blood urea nitrogen, creatinine, eGFR, iPTH, and sclerostin)
  3. HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, iPTH intact parathyroid hormone
  4. *Values of p < 0.05 were considered statistically significant
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