Fig. 2

The relative expression of SK2, SK3, and pERK proteins in the atria of rats from the Con, DM, Met, and PMA groups. Representative Western blots [SK2 (a), SK3 (c), and pERK (e)] and relative histograms [SK2 (b), SK3 (d), and pERK (f)] demonstrate the effects of T2DM, 8-week metformin treatment as well as 2-week injection of PMA on the expression of SK2, SK3, and pERK in rat atria among the four groups (n = 4–5). ^*P < 0.05, ^**P < 0.01 vs Con; ^##P < 0.01 vs DM; ⁺P < 0.05, ⁺⁺P < 0.01 vs Met