Fig. 2

Sleep difficulties and mean values of neuroendocrine and coagulation measures. The bar graphs illustrate the significant differences in norepinephrine (p = 0.010) and fibrinogen (p = 0.003) levels between subjects with poor sleep (i.e., sleep difficulties on more than 7 days in the previous 4 weeks; n = 52) and those with good sleep (n = 138), expressed as geometric mean values with 95% confidence interval. Adjustments were made for age, sex, education, Charlson comorbidity index, positive history of hypertension/high cholesterol/depression, body mass index, smoking, alcohol consumption, physical activity, previous myocardial infarction (MI), ST-segment MI, number of stenotic coronary arteries, Global Registry of Acute Coronary Events risk score, acute distress, and risk of obstructive sleep apnea