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Table 3 Age-standardized incidence rate of CV/heart diseases in secondary prevention among statin users and statin non-users

From: Time trends in statin use and incidence of recurrent cardiovascular events in secondary prevention between 1999 and 2013: a registry-based study

Group ASIR of CV/heart disease in 1999 Summary Trend 1 Trend2
AAPC Years APC Years APC
Total 51.7‰ −3.9 [− 7.4; − 0.4]* 1999–2001 − 13.7 [− 34.4; 13.5] 2001–2013 −2.2 [− 3.8; − 0.6]*
Statin users 69.5‰ −3.4 [− 6.7; 0.1] 1999–2001 − 34.5 [− 62.6; 14.7] 2001–2013 −0.4 [− 3.7; 2.9]
 50–59a 28.3‰a 2.6 [−4.3; 9.9] 2001–2013 2.6 [− 4.3; 9.9]   
 60–79 37.3‰ −0.5 [− 2.8; 1.9] 1999–2013 −0.5 [− 2.8; 1.9]   
 80 + b 55.9‰b −7.2 [− 29.0; 21.3] 2004–2013 −7.2 [− 29.0; 21.3]   
Statin non-users 52.6‰ −3.2 [−4.4; − 2.0]* 1999–2001 − 14.1 [− 33.8; 11.6] 2001–2013 − 2.3 [− 3.8; − 0.8]*
 50–59 37.3‰ −1.8 [−6.7; 3.3] 1999–2013 − 1.8 [− 6.7; 3.3]   
 60–79 51.7‰ −3.2 [− 4.6; − 1.7]* 1999–2013 −3.2 [− 4.6; − 1.7]*   
 80+ 64.2‰ −3.4 [− 5.0; − 1.8]* 1999–2013 −3.4 [− 5.0; − 1.8]*   
  1. *p < 0.05, adata for years 1999 to 2000 were excluded because of the small sample size (N < 100), bdata for years 1999 to 2003 were excluded because of the small sample size (N < 100), ASIR age-standardized incidence rate, AAPC average annual percentage change, APC annual percentage change