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Fig. 1 | BMC Cardiovascular Disorders

Fig. 1

From: Receptor tyrosine kinase profiling of ischemic heart identifies ROR1 as a potential therapeutic target

Fig. 1

Regulation of RTK expression in acute myocardial infarction and ischemic cardiomyopathy. Messenger RNA expression of 52 RTKs in human tissue samples representing healthy heart (n = 62), ischemic cardiomyopathy (n = 63), or acute myocardial infarction (n = 12) was analyzed in silico using IST Online database. a A dotplot presentation of FDR-corrected P values vs. the fold changes of RTK expression levels between samples representing ischemic cardiomyopathy or healthy heart. b A box plot presentation of expression levels of the most significantly up- or downregulated RTKs in ischemic cardiomyopathy vs. healthy heart. c A dotplot presentation of FDR-corrected P values vs. the fold changes of RTK expression levels between samples representing acute myocardial infarction or healthy heart. d A box plot presentation of expression level of the most significantly downregulated RTK in acute myocardial infarction vs. healthy heart. In A and C, the fold changes of means were calculated from log2-transformed Affymetrix expression values (arbitrary units). Vertical grey lines depict the threshold P = 0.05. RTKs not demonstrating significant (P < 0.05) changes in expression are only depicted by dots without labels

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