Impact of cardiac catheterization timing and contrast media dose on acute kidney injury after cardiac surgery

Table 1 Patients Perioperative Characteristics Stratified by the Interval between Coronary Angiography and Cardiac Surgery

	≤7 days (N = 888)	>7 days (N = 181)	P
Demographic data
Male	538(60.6)	129(71.3)	0.007
Age (year)	61.3 ± 8.1	63.9 ± 8.3	< 0.001
Medical history
Hypertension	364(41.0)	114(63.0)	< 0.001
DM	116(13.1)	56(30.9)	< 0.001
NYHA classification 3–4	686(77.3)	118(65.2)	< 0.001
Laboratory values
Hemoglobin (g/L)	131.5 ± 15.1	130.9 ± 141.3	0.685
Albumin(g/L)	40.2 ± 3.5	39.8 ± 3.7	0.184
Kidney function
Serum creatinine (mg/dl)	81.9 ± 24.5	85.8 ± 25.0	0.055
eGFR (ml/min/1.73m²)	83.8 ± 19.5	81.8 ± 20.8	0.227
eGFR< 60 ml/min/1.73m²	80(9.1)	24(13.9)	0.069
Angiographic values
Interval between angiography and surgery (day)	3.2(1.9)	9.7(2.7)	< 0.001
^aContrast media dose (ml/kg)	280(231,349)	285(246,342)	0.198
Surgical data
Valve	692(77.2)	40(22.1)	< 0.001
CABG	151(17.0)	131(72.4)	< 0.001
Valve & CABG	45(5.1)	10(5.5)	0.326
CPB	705(79.4)	57(31.5)	< 0.001
^aCPB time (min)	100(75,127)	90(70,119)	0.106
^bErythrocyte transfusion	441(49.6)	75(41.4)	0.149
Prognosis
AKI	374(42.1)	38(21.0)	< 0.001
KDIGO 1	305(34.3)	29(16.0)	< 0.001
KDIGO 2	45(5.1)	8(4.5)	0.286
KDIGO 3	24(2.7)	1(0.6)	< 0.001
RRT	16(1.8)	4(2.2)	0.762
In-hospital mortality	2(0.2)	1(0.6)	0.427
^aLength of ICU stay (day)	40(22,64)	42(22,70)	0.861
^aLength of hospital stay (day)	14(11,18)	12(11,15)	< 0.001

AKI Acute kidney injury, DM diabetes mellitus, NYHA New York Heart Association, eGFR estimated glomerular filtration rate, calculated by CKD-EPI formulae, CABG coronary artery bypass grafting, CPB cardiopulmonary bypass, KDIGO kidney disease: improving global outcomes, RRT renal replacement therapy, ICU intensive care unit
P-values are the results of unpaired t-test or Mann–Whitney U test for continuous variables, and × 2 test or Fisher’s exact test for categorical variables
^aThe values are expressed as the median (IQR)
^b The amount of erythrocyte transfusion refers to the amount of transfusion during both intraoperative and postoperative on the day of surgery

ISSN: 1471-2261