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Table 2 Intensity of immunoreaction against CB1, CB2, apelin and S100A6 in women heart (mean ± SE). (Scale from 0 (white pixel) to 256 (black pixel))

From: Comparative evaluation of cannabinoid receptors, apelin and S100A6 protein in the heart of women of different age groups

Intensity of immunohistochemical reaction in women heart

women under 50 years old

women over 50 years old

 

CB1

 cardiomyocyte cytoplasm

146.7 ± 2.99

108.2 ± 2.45*

↓*

 intercalated discs

ND

180.7 ± 4.63*

↑*

 endothelium of coronary vessels

61.6 ± 2.16

45.7 ± 2.43*

↓*

CB2

 cardiomyocyte cytoplasm

110.7 ± 2.57

91.1 ± 3.57*

↓*

 endothelium of coronary vessels

49.9 ± 2.15

48.1 ± 1.98

 

apelin

 cardiomyocyte cytoplasm

73.6 ± 2.26

95.0 ± 2.72*

↑*

 endothelium of coronary vessels

135.9 ± 3.65

73.9 ± 2.43*

↓*

S100A6

 cardiomyocyte cytoplasm

81.0 ± 1.85

125.9 ± 3.30*

↑*

 endothelium of coronary vessels

97.4 ± 3.84

79.1 ± 2.48*

↓*

  1. *p < 0.05 women over 50 vs women under 50
  2. ↓ weakening of immunohistochemical reaction
  3. ↑ intensification of immunohistochemical reaction
  4. ND not detected