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Table 1 Baseline Characteristics of the study population, median (IQR), or N (%), or means±SD

From: Value of the fT3/fT4 ratio and its combination with the GRACE risk score in predicting the prognosis in euthyroid patients with acute myocardial infarction undergoing percutaneous coronary intervention: a prospective cohort study

Variable

All Patients (n = 953)

Survival Group (n = 915)

Death Group (n = 38)

p value

Demographics

 Age, yrs

61.0 ± 11.6

60.8 ± 11.6

67.6 ± 10.6

<0.001

 Female

246 (25.8)

231 (25.2)

15 (39.5)

0.050

Medical history

 History of Diabetes Mellitus

281 (29.5)

269 (29.4)

12 (31.6)

0.773

 History of Hypertension

533 (55.9)

502 (54.9)

31 (81.6)

0.001

 History of MI

107 (11.2)

102 (11.1)

5 (13.2)

0.701

 Prior PCI

90 (9.4)

89 (9.7)

1 (2.6)

0.143

Presentation

 Killip class III/IV on admission

19 (2.0)

11 (1.2)

8 (30.0)

<0.001

 SBP on admission, mm Hg

134.4 ± 22.7

134.3 ± 22.6

138.5 ± 26.2

0.259

 Heart rate on admission, bpm

76.6 ± 14.7

76.2 ± 14.3

86.4 ± 20.4

<0.001

 GRACE score

127.7 ± 32.2

126.5 ± 31.6

158.0 ± 32.7

<0.001

Diagnosis on admission

   

0.573

 STEMI

519 (54.5)

500 (54.6)

19 (50.0)

 

 NSTEMI

434 (45.5)

415 (45.4)

19 (50.0)

 

 Troponin-I on admission, ng/mL

4.06 (0.38, 31.77)

4.04 (0.37, 32.07)

5.31 (0.67, 25.01)

0.870

 Creatinine on admission, umol/l

72 (61, 86)

72 (61, 86)

81 (62, 107)

0.090

 Albumin on admission, g/L

39.4 ± 3.6

39.5 ± 3.5

37.5 ± 4.2

0.001

 TSH, uIU/mL

1.546 ± 0.961

1.549 ± 0.965

1.485 ± 0.853

0.687

 fT3, pmol/L

3.902 ± 0.588

3.913 ± 0.581

3.659 ± 0.694

0.009

 fT4, pmol/L

13.11 ± 1.84

13.08 ± 1.82

14.02 ± 2.20

0.002

 fT3/ fT4 ratio

0.302 ± 0.055

0.304 ± 0.054

0.262 ± 0.058

<0.001

Percutaneous coronary intervention details

 Left main disease

75 (7.9)

71 (7.8)

4 (10.5)

0.535

 Three-vessel disease

242 (25.4)

232 (25.4)

10 (26.3)

0.894

 TIMI flow grade 0/1 on arrival

741 (77.8)

714 (78.0)

27 (71.1)

0.311

 TIMI flow grade 3 post PCI

947 (99.4)

910 (99.5)

37 (97.4)

0.111

Medical treatment at discharge

 Aspirin

950 (99.7)

912 (99.7)

38 (100)

0.724

 Clopidogrel

865 (90.8)

830 (90.7)

35 (92.1)

0.771

 Ticagrelor

75 (7.9)

72 (7.9)

3 (7.9)

0.995

 Statin

943 (99.0)

905 (98.9)

38 (100)

0.517

 ACEI/ARB

510 (53.5)

490 (53.6)

20 (52.6)

0.911

 Beta-blockers

481 (50.5)

461 (50.4)

20 (52.6)

0.786

  1. MI myocardial infarction, PCI percutaneous coronary intervention, SBP systolic blood pressure, bpm beats per minute, STEMI ST-segment elevation myocardial infarction, NSTEMI non-ST-segment elevation myocardial infarction, TSH thyrotropin, fT3 free triiodothyronine, fT4 free thyroxine, ACEI/ARB Angiotensin-converting enzyme inhibitors / Angiotensin receptor blockers