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Table 4 Reclassification table using PTP categories < 15%, 15–85%, and > 85% (Individuals with 1 RF)

From: Coronary calcium score improves the estimation for pretest probability of obstructive coronary artery disease and avoids unnecessary testing in individuals at low extreme of traditional risk factor burden: validation and comparison of CONFIRM score and genders extended model

PTP category based on GEM PTP category based on CONFIRM score Total Reclassificationa NRIb P value for NRI
Low Medium High Up Down
Negative individuals      16.64% 36.06% 21.1% < 0.0001
 Low 418 592 11 1021     
 Medium 252 410 32 694     
 High 15 26 5 46     
Total 685 1028 48 1761     
Positive individualsc      13.15% 11.47%   
 Low 19 46 5 70     
 Medium 11 439 24 474     
 High 3 72 35 110     
Total 33 557 64 654     
  1. Abbreviations as in Table 3
  2. aIndividuals was reclassified by GEM and was compared to CONFIRM score
  3. bNRI = [P(Up|Positive)- P(Down|Positive)]-[P(Up|Negative)- P(Down|Negative)]
  4. cPositive individuals was defined as those had at least one lesion with ≥50% diameter stenosis or any non-assessable segments due to severe calcification on CCTA