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Table 3 Reclassification table using PTP categories < 15%, 15–85%, and > 85% (Individuals with 0 RF)

From: Coronary calcium score improves the estimation for pretest probability of obstructive coronary artery disease and avoids unnecessary testing in individuals at low extreme of traditional risk factor burden: validation and comparison of CONFIRM score and genders extended model

PTP category based on GEM PTP category based on CONFIRM score   Reclassificationa NRIb p value for NRI
Low Medium High Total Up Down   
Negative individuals      8.59% 32.10% 29.85% < 0.0001
 Low 300 260 3 563     
 Medium 66 196 6 268     
 High 3 3 1 7     
Total 369 459 10 838     
Positive individualsc      17.63% 11.29%   
 Low 11 15 5 31     
 Medium 6 235 21 262     
 High 1 57 12 70     
Total 18 307 38 363     
  1. NRI net reclassification improvement; other abbreviations as in Table 1
  2. aIndividuals was reclassified by GEM and was compared to CONFIRM score
  3. bNRI = [P(Up|Positive)- P(Down|Positive)]-[P(Up|Negative)- P(Down|Negative)]
  4. cPositive individuals was defined as those had at least one lesion with ≥50% diameter stenosis or any non-assessable segments due to severe calcification on CCTA