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Table 2 Discriminations of CONFIRM score and GEM in individuals with 0 and 1 RF

From: Coronary calcium score improves the estimation for pretest probability of obstructive coronary artery disease and avoids unnecessary testing in individuals at low extreme of traditional risk factor burden: validation and comparison of CONFIRM score and genders extended model

 

AUC

IDI

Statistic

95% CI

P value

PTP

Statisticb

P value

Positive patientsa

Negative patients

0 RF

 CONFIRM score

0.756

0.731 to 0.781

< 0.0001

44%

18%

5%

< 0.0001

 GEM

0.843

0.820 to 0.866

46%

15%

1 RF

 CONFIRM score

0.762

0.742 to 0.783

< 0.0001

48%

22%

8%

< 0.0001

 GEM

0.823

0.804 to 0.841

55%

21%

  1. AUC area under the receiver operating characteristic curve, IDI integrated discrimination improvement, CI confidence interval, other abbreviations as in Table 1
  2. aObstructive CAD was defined as present if an individuals had at least one lesion with ≥50% diameter stenosis or any non-assessable segments due to severe calcification on CCTA
  3. bCompared to CONFIRM score, the IDI of GEM = [P(GEM|Positive)- P(GEM|Positive)]-[P(CONFIRM score|Negative)- P(CONFIRM score|Negative)]