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Table 1 Baseline characteristics by RF burden and presence of obstructive CAD

From: Coronary calcium score improves the estimation for pretest probability of obstructive coronary artery disease and avoids unnecessary testing in individuals at low extreme of traditional risk factor burden: validation and comparison of CONFIRM score and genders extended model

Characteristic

0 RF

1 RF

Total

Obstructive CADb

P value

Total

Obstructive CAD

P value

N = 1201

Yes(N = 363)

No(N = 838)

 

N = 2415

Yes(N = 654)

No(N = 1761)

 

Agea

56.26 ± 10.61

61.24 ± 10.69

54.10 ± 9.83

< 0.0001

57.20 ± 10.56

61.87 ± 10.13

55.47 ± 10.22

< 0.0001

Male

425 (35)

188 (52)

237 (28)

< 0.0001

1233 (51)

400 (61)

833 (47)

< 0.0001

Diabetes

269 (11)

76 (12)

193 (11)

0.6962

Hypertension

949 (39)

263 (40)

686 (39)

0.5989

Hyperlipidemia

563 (23)

140 (21)

423 (24)

0.1974

Smoking

634 (26)

174 (27)

460 (26)

0.8450

Family history

212 (18)

63 (17)

149 (18)

0.7379

483 (20)

131 (20)

352 (20)

0.9544

Chest pain

   

< 0.0001

   

< 0.0001

 Nonanginal

433 (36)

53 (15)

380 (45)

 

893 (40)

92 (14)

801 (45)

 

 Atypical anginal

599 (46)

165 (45)

394 (47)

 

1048 (43)

314 (48)

734 (42)

 

 Typical anginal

209 (18)

145 (40)

64 (8)

 

474 (20)

247 (38)

227 (13)

 

CCS

   

< 0.0001

   

< 0.0001

 0

548 (46)

64 (18)

484 (58)

 

1134 (47)

94 (14)

1040 (59)

 

 0–100

344 (29)

115 (32)

229 (27)

 

607 (25)

197 (30)

410 (23)

 

 100–400

231 (19)

115 (31)

116 (14)

 

431 (18)

180 (28)

251 (14)

 

  > 400

78 (6)

69 (19)

9 (1)

 

243 (10)

182 (28)

61 (4)

 
  1. Values are presented as n (%) unless stated otherwise
  2. CAD coronary artery disease, CCTA coronary computed tomographic angiography, CCS coronary calcium score, RF risk factor
  3. aYears, mean ± standard deviation
  4. bObstructive CAD was defined as present if an individuals had at least one lesion with ≥50% diameter stenosis or any non-assessable segments due to severe calcification on CCTA