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Table 1 Baseline characteristics by RF burden and presence of obstructive CAD

From: Coronary calcium score improves the estimation for pretest probability of obstructive coronary artery disease and avoids unnecessary testing in individuals at low extreme of traditional risk factor burden: validation and comparison of CONFIRM score and genders extended model

Characteristic 0 RF 1 RF
Total Obstructive CADb P value Total Obstructive CAD P value
N = 1201 Yes(N = 363) No(N = 838)   N = 2415 Yes(N = 654) No(N = 1761)  
Agea 56.26 ± 10.61 61.24 ± 10.69 54.10 ± 9.83 < 0.0001 57.20 ± 10.56 61.87 ± 10.13 55.47 ± 10.22 < 0.0001
Male 425 (35) 188 (52) 237 (28) < 0.0001 1233 (51) 400 (61) 833 (47) < 0.0001
Diabetes 269 (11) 76 (12) 193 (11) 0.6962
Hypertension 949 (39) 263 (40) 686 (39) 0.5989
Hyperlipidemia 563 (23) 140 (21) 423 (24) 0.1974
Smoking 634 (26) 174 (27) 460 (26) 0.8450
Family history 212 (18) 63 (17) 149 (18) 0.7379 483 (20) 131 (20) 352 (20) 0.9544
Chest pain     < 0.0001     < 0.0001
 Nonanginal 433 (36) 53 (15) 380 (45)   893 (40) 92 (14) 801 (45)  
 Atypical anginal 599 (46) 165 (45) 394 (47)   1048 (43) 314 (48) 734 (42)  
 Typical anginal 209 (18) 145 (40) 64 (8)   474 (20) 247 (38) 227 (13)  
CCS     < 0.0001     < 0.0001
 0 548 (46) 64 (18) 484 (58)   1134 (47) 94 (14) 1040 (59)  
 0–100 344 (29) 115 (32) 229 (27)   607 (25) 197 (30) 410 (23)  
 100–400 231 (19) 115 (31) 116 (14)   431 (18) 180 (28) 251 (14)  
  > 400 78 (6) 69 (19) 9 (1)   243 (10) 182 (28) 61 (4)  
  1. Values are presented as n (%) unless stated otherwise
  2. CAD coronary artery disease, CCTA coronary computed tomographic angiography, CCS coronary calcium score, RF risk factor
  3. aYears, mean ± standard deviation
  4. bObstructive CAD was defined as present if an individuals had at least one lesion with ≥50% diameter stenosis or any non-assessable segments due to severe calcification on CCTA