Table 1 Baseline clinical characteristics in Non-CAD and CAD patients
Baseline Characteristics | Non-CAD group | CAD group | p value |
|---|---|---|---|
(n = 342) | (n = 771) | ||
Age (years) | 32.1 ± 3.0 | 31.6 ± 3.4 | 0.033 |
Male, n (%) | 318 (92.2) | 730 (94.4) | 0.149 |
Hyperuricemia, n (%) | 104 (30.4) | 285 (37.0) | 0.034 |
Alcohol drinking, n (%) | 86 (24.9) | 194 (25.1) | 0.952 |
BUN(mg/dL) | 14.2 ± 7.8 | 12.4 ± 4.8 | < 0.001 |
Serum creatinine(mg/dL) | 0.9 ± 0.2 | 0.9 ± 0.2 | 0.278 |
Triglycerides(mg/dL) | 145.3 (102.8–218.8) | 172.8(118.1–250.5) | < 0.001 |
HDL-C(mg/dL) | 38.1 ± 9.2 | 35.0 ± 8.0 | < 0.001 |
LDL-C (mg/dL) | 109.0 ± 32.3 | 114.7 ± 46.8 | 0.043 |
Total cholesterol (mg/dL) | 173.4 ± 41.7 | 179.2 ± 55.5 | 0.084 |
Uric acid (mg/dL) | 6.4 ± 1.6 | 6.6 ± 1.6 | 0.194 |
Fasting glucose (mg/dL) | 96.8 ± 26.3 | 104.3 ± 33.0 | < 0.001 |
BMI(kg/m2) | 26.8 ± 4.2 | 27.9 ± 4.1 | < 0.001 |
Traditional coronary risk factor, n (%) | |||
Current smokers, n (%) | 198 (57.4) | 527 (68.2) | < 0.001 |
Family history of CAD, n (%) | 33 (9.6) | 113 (14.6) | 0.021 |
Hypertension, n (%) | 135 (39.1) | 324 (41.9) | 0.382 |
Diabetes mellitus, n (%) | 32 (9.3) | 124 (16.0) | 0.003 |
Metabolic syndrome, n (%) | 168 (49.4) | 450 (58.9) | 0.003 |
Hypercholesterolemia, n (%) | 74 (21.7) | 208 (27.2) | 0.055 |
Hypertriglyceridemia, n (%) | 163 (47.8) | 464 (60.6) | < 0.001 |
High LDL-C, n (%) | 83 (24.3) | 207 (27.0) | 0.349 |
Low HDL-C, n (%) | 235 (68.9) | 586 (76.5) | 0.008 |
familial hypercholesterolemia, n (%) | 0 (0.0) | 12 (1.6) | 0.020 |
Treatment, n (%) | < 0.001 | ||
Drugs, n (%) | 11 (3.2) | 167 (21.6) | |
Intervention, n (%) | 0 (0.0) | 528 (68.3) | |
CABG, n (%) | 0 (0.0) | 77 (10.0) | |
Aspirin, n (%) | 162 (47.0) | 742 (96.0) | < 0.001 |
Clopidogrel/ticagrelor, n (%) | 48 (13.9) | 639 (82.7) | < 0.001 |
Statin, n (%) | 142 (41.2) | 743 (96.1) | < 0.001 |
β-blocker, n (%) | 103 (29.9) | 630 (81.5) | < 0.001 |