Table 1 Characteristics in population with or without QTc prolongation
Variables | Normal QTc | QTc prolongation | P value |
|---|---|---|---|
n (%) | 9913 (95.9) | 421 (4.1) | |
Age, years | 52.9 ± 10.2 | 58.6 ± 11.0 | < 0.001 |
Gender(%) | |||
Male | 4631 (46.7) | 189 (44.9) | 0.463 |
Female | 5282 (53.3) | 232 (55.1) | |
Race (Han) (%) | 9390 (94.7) | 393 (93.3) | 0.219 |
Current smoking (%) | 3546 (35.8) | 150 (35.6) | 0.953 |
Current drinking (%) | 2303 (23.2) | 110 (26.1) | 0.169 |
Physical activity (%) | |||
Low | 2766 (27.9) | 134 (31.8) | 0.212 |
Moderate | 6590 (66.5) | 264 (62.7) | |
Heavy | 557 (5.6) | 23 (5.5) | |
Body mass index (kg/m2) | 24.6 ± 3.6 | 24.9 ± 3.5 | 0.132 |
waist circumference (cm) | 81.9 ± 9.7 | 83.8 ± 9.5 | < 0.001 |
Diet score | 2.3 ± 1.1 | 2.3 ± 1.1 | 0.451 |
LDL-cholesterol, mmol/L | 2.9 ± 0.8 | 3.0 ± 0.8 | 0.004 |
HDL-cholesterol, mmol/L | 1.4 ± 0.4 | 1.5 ± 0.4 | 0.002 |
Triglycerides, mmol/L | 1.6 ± 1.5 | 1.6 ± 1.3 | 0.741 |
Total cholesterol (mmol/L) | 5.2 ± 1.1 | 5.3 ± 1.1 | 0.017 |
Fasting glucose, mmol/L | 5.8 ± 1.6 | 6.1 ± 2.2 | 0.06 |
Systolic blood pressure, mmHg | 139.2 ± 22.0 | 152.8 ± 27.6 | < 0.001 |
Diastolic blood pressure, mmHg | 81.2 ± 11.3 | 83.9 ± 13.8 | < 0.001 |
Estimated GFR (mL/min/1.73m2) | 94.3 ± 14.3 | 92.0 ± 13.9 | 0.001 |
Serum uric acid, mmol/L | 287.4 ± 82.0 | 293.0 ± 84.5 | 0.176 |
Serum sodium, mmol/L | 141.2 ± 2.2 | 141.4 ± 2.4 | 0.124 |
Serum potassium, mmol/L | 4.2 ± 0.3 | 4.1 ± 0.4 | < 0.001 |
Serum calcium, mmol/L | 2.32 ± 0.1 | 2.34 ± 0.1 | < 0.001 |
Serum magnesium, mmol/L | 0.8 ± 0.1 | 0.9 ± 0.1 | 0.022 |
LVMIht2.7, g/m2.7a | 39.2 ± 28.3 | 43.1 ± 12.5 | 0.005 |
QTc Fredericia, ms | 415.6 ± 18.8 | 470.1 ± 23.1 | < 0.001 |
QRS duration> 120 ms | 117 (1.2) | 67 (15.9) | < 0.001 |