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Table 6 Association analysis of rs7396366 genotypes between ACS and SCAD cases

From: A genetic variant near adaptor-related protein complex 2 alpha 2 subunit gene is associated with coronary artery disease in a Chinese population

Genotypes SCAD cases (n = 282) ACS cases (n = 53) OR (95% CI) P Multiple adjusted OR a (95% CI) P
n (%) n (%)
Rs7396366
 GG 136 (48.2) 26 (49.1) 1.03 (0.58–1.86) .912 1.10 (0.60–2.04) .755
 GT 105 (37.2) 22 (41.5) 1.20 (0.66–2.17) .556 1.25 (0.67–2.33) .484
 TT 241 (14.5) 5 (9.4) 0.61 (0.23–1.63) .322 0.49 (0.18–1.36) .172
 Additive model    0.64 (0.23–1.76) .525 0.47 (0.18–1.38) .170
 Dominant model    0.97 (0.54–1.74) .912 0.91 (0.49–1.68) .755
Additive model: TT vs. GG. Dominant model: (TT + GT) vs. GG
  1. aLogistic regression model, adjusted by age, sex, hypertension, T2DM, smoking, BMI, and fasting plasma glucose