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Table 6 Association analysis of rs7396366 genotypes between ACS and SCAD cases

From: A genetic variant near adaptor-related protein complex 2 alpha 2 subunit gene is associated with coronary artery disease in a Chinese population

Genotypes

SCAD cases (n = 282)

ACS cases (n = 53)

OR (95% CI)

P

Multiple adjusted OR a (95% CI)

P

n (%)

n (%)

Rs7396366

 GG

136 (48.2)

26 (49.1)

1.03 (0.58–1.86)

.912

1.10 (0.60–2.04)

.755

 GT

105 (37.2)

22 (41.5)

1.20 (0.66–2.17)

.556

1.25 (0.67–2.33)

.484

 TT

241 (14.5)

5 (9.4)

0.61 (0.23–1.63)

.322

0.49 (0.18–1.36)

.172

 Additive model

  

0.64 (0.23–1.76)

.525

0.47 (0.18–1.38)

.170

 Dominant model

  

0.97 (0.54–1.74)

.912

0.91 (0.49–1.68)

.755

Additive model: TT vs. GG. Dominant model: (TT + GT) vs. GG

  1. aLogistic regression model, adjusted by age, sex, hypertension, T2DM, smoking, BMI, and fasting plasma glucose