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Table 2 Clinical characteristics in controls and CAD subgroups

From: A genetic variant near adaptor-related protein complex 2 alpha 2 subunit gene is associated with coronary artery disease in a Chinese population

Variables CAD (n = 335) subgroups Controls (n = 372)
SCAD(n = 282) P NSTEMI(n = 28) P STEMI(n = 25) P
n (%) n (%) n (%) n (%)
Age (years) 66.44 ± 10.98 < 0.001 69.46 ± 11.21 < 0.001 66.04 ± 11.20 0.001 58.11 ± 11.53
Sex (male) 159 (56.4) 0.018 22 (78.6) 0.001 15 (60.0) 0.222 175 (47.0)
BMI (kg/m2) 25.53 ± 3.70 0.227 25.34 ± 4.37 0.826 23.07 ± 2.78 0.054 25.09 ± 4.39
Smoking, n (%) 80 (28.4) 0.730 15 (53.6) 0.005 10 (40.0) 0.172 101 (27.2)
Hypertension, n (%) 215 (76.2) < 0.001 17 (60.7) 0.845 13 (46.4) 0.538 217 (58.3)
Total cholesterol(mmol/L) 4.49 ± 1.26 0.239 4.41 ± 1.14 0.464 4.51 ± 1.11 0.689 4.64 ± 1.55
T2DM, n (%) 71 (25.2) 0.002 11 (39.3) 0.003 10 (40.0) 0.004 58 (15.6)
Fasting plasma glucose (mmol/L) 5.97 (1.66) 0.038 6.40 ± 1.65 0.027 6.75 ± 2.65 0.061 5.70 ± 1.62
Number of vessels involved, n (%)
 one 163 (57.8)   6 (21.4)   4 (16.0)   
 two 67 (27.8)   10 (35.7)   8 (32.0)   
 three 52 (18.4)   12 (42.9)   13 (52.0)   
  1. Abbreviations: SCAD stable coronary artery disease, STEMI ST-segment elevation myocardial infarction, NSTEMI non-ST-elevation myocardial infarction. Other abbreviations list in Table 1
  2. Age, BMI, total cholesterol and fasting plasma glucose are expressed as the mean ± SD and were compared using the Student t test. Other data are expressed as frequencies and percentages and were compared using the χ2-test