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Table 2 Clinical characteristics in controls and CAD subgroups

From: A genetic variant near adaptor-related protein complex 2 alpha 2 subunit gene is associated with coronary artery disease in a Chinese population

Variables

CAD (n = 335) subgroups

Controls (n = 372)

SCAD(n = 282)

P

NSTEMI(n = 28)

P

STEMI(n = 25)

P

n (%)

n (%)

n (%)

n (%)

Age (years)

66.44 ± 10.98

< 0.001

69.46 ± 11.21

< 0.001

66.04 ± 11.20

0.001

58.11 ± 11.53

Sex (male)

159 (56.4)

0.018

22 (78.6)

0.001

15 (60.0)

0.222

175 (47.0)

BMI (kg/m2)

25.53 ± 3.70

0.227

25.34 ± 4.37

0.826

23.07 ± 2.78

0.054

25.09 ± 4.39

Smoking, n (%)

80 (28.4)

0.730

15 (53.6)

0.005

10 (40.0)

0.172

101 (27.2)

Hypertension, n (%)

215 (76.2)

< 0.001

17 (60.7)

0.845

13 (46.4)

0.538

217 (58.3)

Total cholesterol(mmol/L)

4.49 ± 1.26

0.239

4.41 ± 1.14

0.464

4.51 ± 1.11

0.689

4.64 ± 1.55

T2DM, n (%)

71 (25.2)

0.002

11 (39.3)

0.003

10 (40.0)

0.004

58 (15.6)

Fasting plasma glucose (mmol/L)

5.97 (1.66)

0.038

6.40 ± 1.65

0.027

6.75 ± 2.65

0.061

5.70 ± 1.62

Number of vessels involved, n (%)

 one

163 (57.8)

 

6 (21.4)

 

4 (16.0)

  

 two

67 (27.8)

 

10 (35.7)

 

8 (32.0)

  

 three

52 (18.4)

 

12 (42.9)

 

13 (52.0)

  
  1. Abbreviations: SCAD stable coronary artery disease, STEMI ST-segment elevation myocardial infarction, NSTEMI non-ST-elevation myocardial infarction. Other abbreviations list in Table 1
  2. Age, BMI, total cholesterol and fasting plasma glucose are expressed as the mean ± SD and were compared using the Student t test. Other data are expressed as frequencies and percentages and were compared using the χ2-test