Table 5 Primary and second outcomes of the Included Trials

BIO-RESORT

target vessel failure at 12 months

target lesion failure, death, myocardial infarction, coronary revascularization, major adverse cardiac events, patient-oriented composite endpoint, definite or probable stent thrombosis

BIOFLOW II

in-stent late lumen loss at 9 months

in-segment late lumen loss and in-stent and in-segment minimal luminal diameter, percent diameter stenosis, and binary restenosis. Cardiac death, procedure-related deaths, myocardial infarction, target-lesion revascularization.

BIOFLOW V

target lesion failure at 12 months

major adverse cardiac events (all-cause death, myocardial infarction or ischemia-driven target lesion revascularization), target vessel failure, the individual components of the composite endpoints at 30 days and 12 months, and definite or probable stent thrombosis according to academic research consortium (arc) criteria.

BIOSCIENCE

target-lesion failure at 12 months

all-cause death, cardiac death, myocardial infarction, target vessel mi, coronary revascularization, major adverse cardiac events, patient-oriented composite endpoint, stent thrombosis, target lesion revascularization, target vessel revascularization, repeat revascularization, target vessel failure, cerebrovascular event

ORIENT

in-stent late lumen loss at 9 months,

in-segment late lumen loss, percentage diameter stenosis, and binary restenosis at 9 months; all-cause death, cardiac death, myocardial infarction, repeat revascularization, ischemic stroke, hemorrhagic stroke, bleeding, stent thrombosis, target lesion failure, target vessel failure

PRISON IV

in-segment late lumen loss at 9 months

in-stent late lumen loss, in-stent and in-segment percentage of diameter stenosis, binary restenosis, and re-occlusions at 9 months; clinically indicated target lesion, revascularization or target vessel revascularization, myocardial infarction, death (cardiac and noncardiac), stent thrombosis, target vessel failure, and major adverse cardiac events.