Table 2 GRADE evidence profile of outcomes, O-SES versus DP-DES
Outcome | No. of patients (Studies) | Study results (95% CI) and measurements | Absolute effect estimates (per 1000) | Quality | Importance | |||
|---|---|---|---|---|---|---|---|---|
O-SES | DP-DES | O-SES | DP-DES | Absolute Risk (95% CI) | ||||
Myocardial infarction | 142/3777 (3.8%) | 147/3095 (4.7%) | RR 0.78 (0.62 to 0.98) | 37 | 47 | 10 fewer (from 1 fewer to 18 fewer) | ⊕ ⊕ ⊕ ⊕ High | Critical |
Stent thrombosis | 50/3767 (1.3%) | 63/3095 (2%) | RR 0.75 (0.52 to 1.08) | 15 | 20 | 5 fewer (from 10 fewer to 2 more) | ⊕ ⊕ ⊕⊝ Moderatea | Important |
Cardiac death | 50/3777 (1.3%) | 50/3095 (1.6%) | RR 0.93 (0.63 to 1.36) | 15 | 16 | 1 fewer (from 6 fewer to 6 more) | ⊕ ⊕ ⊕⊝ Moderatea | Important |
Target vessel revascularization | 166/3778 (4.4%) | 141/3092 (4.6%) | RR 0.97 (0.78 to 1.21) | 45 | 46 | 1 fewer (from 10 fewer to 10 more) | ⊕ ⊕ ⊕ ⊕ High | Important |
Target lesion revascularization | 129/3777 (3.4%) | 101/3094 (3.3%) | RR 1.1 (0.86 to 1.42) | 36 | 33 | 3 more (from 5 fewer to 14 more) | ⊕ ⊕ ⊕ ⊕ High | Important |