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Table 1 Sociodemographic and medical factors in coronary patients with normal blood glucose, prediabetes and type 2 diabetes

From: Managing patients with prediabetes and type 2 diabetes after coronary events: individual tailoring needed - a cross-sectional study

 

Normal blood glucose

Prediabetes

Type 2 diabetes

P-Value

 

(n = 356, 32.4%)

(n = 484, 44.1%)

(n = 243, 22.4%)

Normal blood glucose vs. prediabetes

Type 2 diabetes vs. prediabetes

Socio-demographic factors

Age in years at index event, mean (SD)

59.4 (9.9)

63.3 (8.9)

62.3 (9.1)

***

N.S.

Number of months from index event to follow-up, mean (SD)

16.2 (10.3)

17.0 (10.5)

18.3 (10.5)

N.S.

N.S.

Female sex, n (%)

69 (19.4)

108 (22.3)

49 (20.2)

N.S.

N.S.

Ethnic minority, n (%)a

5 (1.4)

10 (2.1)

18 (7.4)

N.S.

***

Living alone, n (%)

57 (16.0)

84 (17.4)

50 (21.7)

N.S.

N.S.

Low education, n (%)b

221 (62.1)

346 (71.5)

181 (76.1)

**

N.S.

Medical factors

Coronary index diagnosis, n (%)

 Non-ST elevation myocardial infarction

170 (47.8)

247 (51.0)

123 (40.1)

N.S.

*

 ST-elevation myocardial infarction

111 (31.1)

148 (30.6)

58 (23.9)

N.S.

N.S.

 Stable or unstable angina

75 (21.1)

89 (18.4)

62 (25.5)

N.S.

N.S.

> 1 coronary event prior to the index event, n (%)

91 (25.6)

119 (24.6)

113 (46.5)

N.S.

***

Participation in cardiac rehabilitation, n (%)

183 (51.4)

206 (42.6)

139 (57.2)

*

***

Charlson co-morbidity score, mean (SD)

3.6 (1.4)

4.1 (1.3)

4.8 (1.5)

***

***

Chronic kidney disease (eGFR < 60), n (%)

30 (8.4)

58 (12.0)

45 (20.3)

N.S.

*

Antidepressant medication at the time of the index event, n (%)

16 (4.5)

16 (3.3)

21 (8.6)

N.S.

**

Coronary risk factors and medication at interview

 Low density lipoprotein cholesterol mmol/L, mean (SD)

2.15 (0.73)

2.09 (0.80)

2.07 (0.84)

N.S.

N.S.

 Low density lipoprotein cholesterol ≥1.8 mmol/L, n (%)

222 (62.4)

273 (56.4)

122 (51.0)

N.S.

N.S.

 High density lipoprotein cholesterol mmol/L, mean (SD)

1.19 (0.34)

1.16 (0.32)

1.02 (0.30)

N.S.

***

 Current smoking, n (%)

49 (13.8)

115 (23.8)

53 (22.7)

***

N.S.

 C-reactive protein in mg/L, mean (SD)

2.06 (2.13)

2.37 (2.73)

3.22 (2.89)

N.S.

***

 C-reactive protein ≥2 mg/L, n (%)

123 (35.5)

172 (36.6)

131 (56.5)

N.S.

***

 Physical activity < 30 min of moderate activity 2–3 times a week, n (%)

158 (44.5)

227 (48.4)

129 (54.2)

N.S.

N.S.

 Physical activity < 1 time a week, n (%)

53 (14.9)

73 (15.1)

59 (24.9)

N.S.

**

 Blood pressure ≥ 140/90 (80 in diabetes) mmHg, n (%)

118 (33.1)

198 (44.0)

129 (60.6)

***

***

 Waist circumference, mean (SD)

100.1 (11.1)

101.3 (12.1)

108.5 (12.6)

N.S.

***

 Waist circumference ≥ 102/88 cm in men/women, n (%)

168 (51.5)

258 (57.5)

164 (76.6)

N.S.

***

 Body Mass Index ≥30 kg/m2, n (%)

84 (23.6)

133 (27.5)

116 (54.2)

N.S.

***

 Fruit and vegetables < 2 units/day, n (%)

132 (37.6)

187 (38.6)

92 (39.7)

N.S.

N.S.

 Fish meals < 3 times/week, n (%)

171 (48.0)

213 (44.0)

118 (48.6)

N.S.

N.S.

Medication at interview, n (%)

 Statin, n (%)

332 (93.3)

451 (93.2)

224 (92.2)

N.S.

N.S.

 High-intensity statin therapy, n (%)

168 (47.2)

247 (51.0)

104 (55.9)

N.S.

N.S.

 Aspirin, n (%)

351 (98.6)

467 (96.5)

235 (96.7)

N.S.

N.S.

 Beta-blockers, n (%)

248 (69.7)

349 (72.1)

188 (77.4)

N.S.

N.S.

 ACE-inhibitors or ARB, n (%)

166 (46.6)

232 (47.9)

143 (58.8)

N.S.

**

Low Morisky Scorec, n (%)

38 (10.7)

40 (8.3)

22 (9.6)

N.S.

N.S.

  1. SD standard deviation, NS not significant, eGFR estimated glomerular filtration rate, ACE angiotensin converting enzyme, ARB angiotensin receptor blocker. *p < 0.05, **p < 0.01, ***p < 0.001
  2. aEthnic minority was defined as 1st and 2nd generation patients born in Asia, Africa and South America
  3. bLow education was defined as completion of primary and secondary school only
  4. cScores: > 2 on the Morisky 8-item medication adherence questionnaire, indicating low adherence