Plasma levels of soluble VEGF receptor isoforms, circulating pterins and VEGF system SNPs as prognostic biomarkers in patients with acute coronary syndromes

Table 5 Cox’s proportional hazards regression model for mortality in the subgroup of the CDCS cohort assayed for pterins (n = 138, 32 deaths)

	Coefficient	SE	Wald	df	Significance	Hazard Ratio	95% CI for HR
	Coefficient	SE	Wald	df	Significance	Hazard Ratio	Lower	Upper
Age at baseline	0.06	0.02	7.20	1	0.007	1.06	1.02	1.10
Log₁₀ NTpro-BNP at baseline^a	1.28	0.53	5.87	1	0.015	3.59	1.28	10.1
Log₁₀s-Flt-1 at baseline^a	3.06	1.38	4.87	1	0.027	21.2	1.41	319
Log₁₀Total pterins at baseline^a	2.16	0.54	16.3	1	< 0.001	8.70	3.04	24.9
Time to sampling^b	0.004	0.02	0.04	1	0.847	1.00	0.97	1.05

^aHazard Ratio represents the change in risk for every 10-fold increase in analyte level
^bDays between index hospital admission and plasma sampling

ISSN: 1471-2261