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Table 2 Predictors of medication non-adherence among hypertensive patients in univariate and multivariate logistic regression

From: Non-adherence to antihypertensive pharmacotherapy in Buea, Cameroon: a cross-sectional community-based study

Variables Non-adherent OR 95% CI p-value AOR 95% CI p-value
Yes (N = 122) No (N = 61)
Age (in years) Mean (SD) 57.0 (12.3) 53.8 (12.2) 1.02 1.0–1.04 0.108 1.02 0.98–1.06 0.264
Gender
 Male 48 (39.3) 17 (26.2) 1.7 0.9–3.3 0.128 1.1 0.4–2.6 0.814
 Female 74 (60.7) 44 (72.1) Ref      
Marital status
 Single 11 (9.0) 6 (9.8) Ref     
 Married 86 (70.5) 40 (65.6) 0.9 0.3–3.0 0.857    
 Divorced 2 (1.6) 1 (1.6) 0.8 0.4–1.6 0.489    
 Widow/Widower 23 (18.9) 14 (23.0) 0.9 0.1–9.9 0.877    
Level of education
 None 47 (38.5) 25 (41.0) Ref     
 Primary 44 (36.1) 23 (37.7) 1.0 0.5–2.0 0.961    
 Secondary 21 (17.2) 10 (16.4) 1.1 0.5–2.7 0.809    
 Tertiary 10 (8.2) 3 (4.9) 1.8 0.4–7.0 0.415    
Employment status
 Unemployed 63 (51.6) 25 (41.0) 1.5 0.8–2.9 0.175 1.4 0.3–1.6 0.477
 Employed 59 (48.4) 36 (59.0) Ref      
Occupational status
 Low 38 (64.4) 23 (63.9) 0.8 0.3–2.5 0.735   
 Medium 9 (15.3) 7 (19.4) 0.6 0.2–2.6 0.534    
 High 12 (20.3) 6 (16.7) Ref      
Daily dose frequency
 Mean (SD) 1.7 (0.6) 1.4 (0.6) 2.6 1.4–4.6 0.001* 2.5 1.2–5.6 0.021*
Number of antihypertensive
 Mean (SD) 1.7 (0.8) 1.3 (0.6) 2.5 1.4–4.3 0.001* 1.3 0.6–2.9 0.477
Duration of treatment (in years)
 Mean (SD) 3.1 (1.3) 2.8 (1.4) 0.2 0.9–1.5 0.215 0.9 0.7–1.3 0.590
Forgetfulness
 Yes 86 (72.3) 13 (21.7) 10.0 5.1–20.2 <  0.001* 7.9 3.0–20.8 <  0.001*
 No 33 (27.7) 47 (78.3) Ref    Ref   
Lack of funds
 Yes 67 (56.3) 18 (29.5) 3.3 1.7–5.0 0.001* 2.8 1.1–6.9 0.024*
 No 52 (43.7) 43 (70.5) Ref    Ref   
Busy schedule
 Yes 44 (37.0) 8 (13.3) 3.3 1.7–10.1 0.002* 2.0 0.6–6.5 0.247
 No 75 (63.0) 52 (86.7) Ref    Ref   
Experiencing side effects
 Yes 40 (33.6) 3 (4.8) 10.2 2.5–25.1 < 0.001* 7.6 1.7–33.0 0.007*
 No 79 (66.4) 58 (95.1) Ref    Ref   
Belief in the efficacy of the drug
 Yes 102 (85.7) 57 (95.0) 0.3 0.1–1.1 0.075 4.9 0.9–26.9 0.066
 No 17 (14.3) 3 (5.0) Ref    Ref   
Herbs
 Yes 25 (21.0) 13 (22.0) 1.1 0.5–2.3 0.875   
 No 94 (79.0) 46 (78.0) Ref      
Taste and smell of the drug
 Yes 1 (1.7) 3 (2.5) 0.7 0.1–6.5 0.717   
 No 59 (98.3) 116 (97.5)       
  1. SD Standard deviation, OR Odds ratio, AOR Adjusted Odd’s ratio, CI Confidence interval
  2. *significant p-value; N = 183; df = 1, p <  0.001, R2 = 0.453