Table 2 Characteristics of included studies

Aoyama et al. 2017 [22]

PAD was diagnosed based on clinical symptoms, ABI, and angiographic fndings

NR

age, sex, smoking, hypertension, dyslipidemia and HbA1c levels

Çalapkorur et al. 2017 [34]

Patients with ABI values of ≤0.90 were diagnosed as having PAD

Periodontitis was defined as the presence of at least five teeth with one or more sites with a PD of ≥5 mm, a CAL of ≥2 mm, the presence of BOP and 30% radiographic bone loss

age, gender, diabetes, hypertension and BMI

Ahn et al. 2016 [27]

PAD was evaluated by using ABI lower than 1.0

The radiographic alveolar bone loss 4 mm at two or more interproximal sites, not on the same tooth

age, sex, education level, tooth loss, smoking, drinking, central obesity

Soto-Barreras et al. 2013 [26]

Patients with ABI values of ≤0.90 were diagnosed as having PAD

The diagnosis of periodontitis was determined when the attachment loss was ≥4 mm in ≥30% of measured sites.

age, sex, BMI,smoking, and diabetes mellitus

Chen et al. 2008 [30]

PAD was diagnosed based on clinical symptoms, ABI, and angiographic fndings

Participants who presented with at least one probing site with PD 4 mm or CAL 4 mm in each quadrant were defined as periodontitis patients

Smoking, age, gender, and diabetes

Bloemenkamp et al. 2002 [33]

PAD was angiographically confirmed when a stenotic lesion causing more than 50% reduction of the lumen was present in at least one major peripheral artery

NR

Smoking, age, gender, and diabetes

Mendez et al. 1998 [25]

PAD was defined as one or more of the following: (1) intermittent claudication; (2) extracranial erebrovascular disease; (3) atherosclerosis (including aortic, renal, and mesenteric disease); and (4) arterial embolism and thrombosis.

Periodontitis was considered present if the mean whole mouth alveolar bone loss was>20%.

age, BMI, family history of heart disease, and smoking exposure