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Table 1 TERT decreased the cardiac expression of ACE but increased the expression of ACE 2 and Ang II in CIH

From: Telmisartan protects chronic intermittent hypoxic mice via modulating cardiac renin-angiotensin system activity

Group n Cardiac ACE Cardiac Ang II Cardiac ACE 2 Apoptotic rate of myocardial cells by TUNEL assay (%)
CIH group 8 0.034900 ± 0.0130a 0.095922 ± 0.0328d 0.052200 ± 0.0192b 53.23 ± 5.292f
ARB treatment group 8 0.025100 ± 0.0061a 0.149025 ± 0.0217d c 0.072850 ± 0.0175b c 23.32 ± 2.827
Blank control group 8 0.004738 ± 0.0026 0.015019 ± 0.0070 0.017488 ± 0.0131 22.39 ± 3.715
Air control group 8 0.005238 ± 0.0026 0.020684 ± 0.0107 0.029313 ± 0.0136 23.72 ± 2.857
  1. ap < 0.001 vs. blank and air control groups
  2. bp < 0.05 vs. blank and air control groups
  3. cp < 0.001 vs. CIH
  4. dp < 0.05 vs. blank and air control groups
  5. ep < 0.05 vs. CIH
  6. fp < 0.001 vs. the other three experimental groups
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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