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Table 1 TERT decreased the cardiac expression of ACE but increased the expression of ACE 2 and Ang II in CIH

From: Telmisartan protects chronic intermittent hypoxic mice via modulating cardiac renin-angiotensin system activity

Group

n

Cardiac ACE

Cardiac Ang II

Cardiac ACE 2

Apoptotic rate of myocardial cells by TUNEL assay (%)

CIH group

8

0.034900 ± 0.0130a

0.095922 ± 0.0328d

0.052200 ± 0.0192b

53.23 ± 5.292f

ARB treatment group

8

0.025100 ± 0.0061a

0.149025 ± 0.0217d c

0.072850 ± 0.0175b c

23.32 ± 2.827

Blank control group

8

0.004738 ± 0.0026

0.015019 ± 0.0070

0.017488 ± 0.0131

22.39 ± 3.715

Air control group

8

0.005238 ± 0.0026

0.020684 ± 0.0107

0.029313 ± 0.0136

23.72 ± 2.857

  1. ap < 0.001 vs. blank and air control groups
  2. bp < 0.05 vs. blank and air control groups
  3. cp < 0.001 vs. CIH
  4. dp < 0.05 vs. blank and air control groups
  5. ep < 0.05 vs. CIH
  6. fp < 0.001 vs. the other three experimental groups
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BMC Cardiovascular Disorders

ISSN: 1471-2261

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