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Fig. 5 | BMC Cardiovascular Disorders

Fig. 5

From: Telmisartan protects chronic intermittent hypoxic mice via modulating cardiac renin-angiotensin system activity

Fig. 5

Pathological changes in myocardial cell mitochondria under electron microscope. Ultrastructural examination was performed as described in materials and methods. a In CIH group the number of mitochondria decreased, the size was abnormal, the mitochondrial membrane was incomplete, the number of cristae was reduced, and the arrangement was disorder. The cristae were broken, dissolved, destroyed, flocculent, and the electron density of matrix increases. b In ARB group, the quantity and size of the mitochondrial are normal and the membrane is intact. The electron density of the mitochondrial matrix increased the same as CIH group while the number of cristae was normal and well arranged. c & d In blank and air control groups, the quantity and size of the mitochondrial are normal and the membrane is intact. The mitochondrial cristae were filled with the entire cavity of the mitochondrion and were arranged in parallel, regular and abundant in number. Magnification: 40000×, scale bar, 1 μm

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