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Table 1 ᅟ

From: Selection of essential medicines for the prevention and treatment of cardiovascular diseases in low and middle income countries

Primary and secondary prevention of cardiovascular diseases

Hypertension treatment

thiazide diuretics, selective β1-blockers, dihydropyridine calcium channel blockers, renin-angiotensin-aldosterone system (RAAS) inhibitors including angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs)

Dyslipidaemia treatment

statins

Platelet inhibition

acetylsalicylic acid, adenosine diphosphate (ADP) receptor inhibitors

Treatment of acute cardiovascular events

Ischemic stroke

thrombolytic agents including streptokinase and urokinase as well as recombinant tissue plasminogen activators (rt-PAs), platelet inhibitors (acetyl salicylic acid or ADP-receptor blockers)

Stable ischemic heart disease

Angina attack treatment: nitroglycerin

Prophylaxis angina pectoris attacks: selective β1-blockers, long-acting nitrates, non-dihydropyridine calcium channel blockers

Acute coronary syndrome

nitrates, morphine, selective β1-blockers, acetyl salicylic acid, ADP-receptor blockers, heparin-like medicines (including unfractionated heparin (UFH) and low molecular weight heparins (LMWH)), thrombolytic agents

Management of further complications of ACS: Ventricular fibrillation: lidocaine, Bradycardia: atropine, Cardiogenic shock: dopamine

Heart failure

loop diuretics, RAAS inhibitors, selective β1-blockers, aldosteron antagonists, digitalis glycosides, dopamine or dobutamine or milrinone

Atrial fibrillation

oral anticoagulants including vitamin K antagonists or direct oral anticoagulants (DOAC)

Frequency control: selective β1-blockers, non-dihydropyridine calcium channel blockers, digitalis glycosides (in case of atrial fibrillation plus heart failure)

Rhythm control:

pharmacological cardioversion: flecainide, dofetilide, propafenone, ibutilide, amiodarone maintaining sinus rhythm: amiodarone, dofetilide, dronedarone, flecainide, propafenone, sotalol

Peripheral arterial disease (Intermittent claudication)

cilostazol or naftidrofuryl (for relief of ischemic complaints)

Acute limb ischemia

heparin, thrombolytic agents, platelet inhibitors