Skip to main content

Table 1 ᅟ

From: Selection of essential medicines for the prevention and treatment of cardiovascular diseases in low and middle income countries

Primary and secondary prevention of cardiovascular diseases Hypertension treatment thiazide diuretics, selective β1-blockers, dihydropyridine calcium channel blockers, renin-angiotensin-aldosterone system (RAAS) inhibitors including angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs)
Dyslipidaemia treatment statins
Platelet inhibition acetylsalicylic acid, adenosine diphosphate (ADP) receptor inhibitors
Treatment of acute cardiovascular events Ischemic stroke thrombolytic agents including streptokinase and urokinase as well as recombinant tissue plasminogen activators (rt-PAs), platelet inhibitors (acetyl salicylic acid or ADP-receptor blockers)
Stable ischemic heart disease Angina attack treatment: nitroglycerin
Prophylaxis angina pectoris attacks: selective β1-blockers, long-acting nitrates, non-dihydropyridine calcium channel blockers
Acute coronary syndrome nitrates, morphine, selective β1-blockers, acetyl salicylic acid, ADP-receptor blockers, heparin-like medicines (including unfractionated heparin (UFH) and low molecular weight heparins (LMWH)), thrombolytic agents
Management of further complications of ACS: Ventricular fibrillation: lidocaine, Bradycardia: atropine, Cardiogenic shock: dopamine
Heart failure loop diuretics, RAAS inhibitors, selective β1-blockers, aldosteron antagonists, digitalis glycosides, dopamine or dobutamine or milrinone
Atrial fibrillation oral anticoagulants including vitamin K antagonists or direct oral anticoagulants (DOAC)
Frequency control: selective β1-blockers, non-dihydropyridine calcium channel blockers, digitalis glycosides (in case of atrial fibrillation plus heart failure)
Rhythm control:
pharmacological cardioversion: flecainide, dofetilide, propafenone, ibutilide, amiodarone maintaining sinus rhythm: amiodarone, dofetilide, dronedarone, flecainide, propafenone, sotalol
Peripheral arterial disease (Intermittent claudication) cilostazol or naftidrofuryl (for relief of ischemic complaints)
Acute limb ischemia heparin, thrombolytic agents, platelet inhibitors