Table 1 Clinical and echocardiographic characteristics according to the occurrence of death during subsequent pregnancy after PPCM
n (%), median (interquartile range), mean ± SD | Total population | Alive patients (n = 15) | Deceased patients (n = 14) | p |
|---|---|---|---|---|
Baseline data | ||||
Age | 26.7 ± 4.6 | 26 ± 5 | 28 ± 6 | 0.44 |
Low socio-economic status | 22 (75.8) | 12 (80) | 9 (64) | 0.43 |
Gravidity | 2.3 ± 0.5 | 2.2 ± 0.6 | 2.4 ± 0.5 | 0.26 |
Baseline LVEF after the first PPCM (%) | 49.9 ± 5.2 | 50 ± 6 | 50 ± 7 | 0.99 |
Baseline LVEF after the PPCM < 50% | 16 (55.2) | 7 (47) | 9 (64) | 0.46 |
Baseline LVEF after the first PPCM < 45% | 5 (17.2) | 2 (13) | 4 (29) | 0.39 |
Baseline LVEDD after the PPCM (mm) | 53.3 ± 3.6 | 54 ± 4 | 53 ± 5 | 0.88 |
Baseline sPAP after the PPCM (mmHg) | 29.2 ± 4.2 | 28 ± 5 | 30 ± 5 | 0.26 |
Baseline TAPSE after the PPCM (mm) | 18.2 ± 2.4 | 19 ± 3 | 17 ± 3 | 0.10 |
Follow-up data (at the time of hospitalization) | ||||
Delay between last follow-up and hospitalization (month) | 17 ± 6 | 15 ± 6 | 18 ± 6 | 0.27 |
Congestive heart failure | 19 (65.5) | 6 (40) | 14(100) | < 0.001 |
LVEF (%) | 37.6 ± 4.7 | 44 ± 6 | 33 ± 6 | < 0.001 |
LVEF < 40% | 14 (48.3) | 2 (13) | 13 (93) | 0.001 |
Delta LVEF (%) | −19.3 ± 9 | - 11 ± 10 | −32 ± 15 | < 0.001 |
LVEDD (mm) | 57.5 ± 3.9 | 59 ± 4 | 56 ± 5 | 0.05 |
Delta LVEDD (%) | 8 ± 6 | 11 ± 11 | 5 ± 7 | 0.09 |
sPAP (mmHg) | 37.9 ± 5.4 | 34 ± 5 | 42 ± 5 | < 0.001 |
Delta sPAP (%) | 19 ± 8 | 17 ± 10 | 27 ± 15 | 0.07 |
TAPSE (mm) | 16.8 ± 3.2 | 19 ± 3 | 14 ± 4 | < 0.001 |
TAPSE < 17 mm | 11 (37.9) | 1 (7) | 10 (71) | < 0.001 |
TAPSE < 18 mm | 13 (44.8) | 2 (13) | 11 (79) | < 0.001 |
Delta TAPSE (%) | - 7.5 ± 5 | 3 ± 17 | −15 ± 27 | 0.03 |
Pregnancy data | ||||
Abortion | 6 (20.6) | 2 (13) | 4 (29) | 0.39 |
Prematurity | 8 (27.6) | 4 (27) | 4 (29) | 1 |
Full-term pregnancy | 51.7 | 9 (60) | 6 (43) | 0.47 |
Newborn weight (g) | 2385 ± 286 | 2350 ± 500 | 2380 ± 300 | 0.90 |