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Table 2 The association of CHD death with neck circumference according to AHI categories

From: The association of neck circumference with incident congestive heart failure and coronary heart disease mortality in a community-based population with or without sleep-disordered breathing

  Quartiles of neck circumference  
Q1 (low) Q2 Q3 Q4 (high) The overall tendency
AHI < 5#
 Subjects, n 805 655 491 283  
 Events, n (%) 10 (1.2) 17 (2.6) 17 (3.5) 14 (4.9)  
 Univariate Model 1 (Ref) 2.120 (0.971–4.631) 2.951 (1.351–6.445) 4.164 (1.849–9.374) 1.117 (1.049–1.189)
 Multivariate Model 1 1 (Ref) 1.622 (0.710–3.705) 2.760 (0.977–7.798) 5.480 (1.574–19.075) 1.141 (1.014–1.282)
 Multivariate Model 2 1 (Ref) 1.629 (0.714–3.717) 2.782 (0.992–7.807) 5.486 (1.624–18.527) 1.139 (1.019–1.274)
 Multivariate Model 3 1 (Ref) 1.914 (0.762–4.807) 3.427 (1.806–10.814) 5.477 (1.422–21.090) 1.134 (1.001–1.284)
AHI ≥ 5*
 Subjects, n 304 455 681 759  
 Events, n (%) 8 (2.6) 18 (4.0) 34 (5.0) 26 (3.4)  
 Univariate Model 1 (Ref) 1.479 (0.643–3.402) 1.886 (0.873–4.074) 1.291 (0.584–2.851) 1.013 (0.962–1.068)
 Multivariate Model 1 1 (Ref) 1.773 (0.749–4.194) 2.115 (0.858–5.215) 1.972 (0.663–5.868) 1.061 (0.979–1.150)
 Multivariate Model 2 1 (Ref) 1.643 (0.690–3.914) 1.891 (0.762–4.690) 1.735 (0.586–5.135) 1.050 (0.968–1.139)
 Multivariate Model 3 1 (Ref) 1.292 (0.504–3.309) 1.538 (0.579–4.087) 1.393 (0.472–4.538) 1.033 (0.944–1.130)
  1. Model 1 adjusted for age, gender, and BMI
  2. Model 2 adjusted for age, gender, BMI, and waist circumference
  3. Model 3 adjusted for age, gender, BMI, waist circumference, AHI, smoking status, total cholesterol, triglycerides, high-density lipoprotein, history of diabetes, and history of hypertension
  4. Results are presented as hazard ratio (95% confidence interval). CHD coronary heart disease, AHI apnoea-hypopnea index, BMI body mass index
  5. #P value for the overall tendency of neck circumference modelled as a continuous variable was 0.001, 0.028, 0.022, and 0.048 in univariate model, multivariate model 1, model 2, and model 3, respectively
  6. *P value for the overall tendency of neck circumference modelled as a continuous variable was 0.616, 0.149, 0.236, and 0.478 in univariate model, multivariate model 1, model 2, and model 3, respectively