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Table 2 The association of CHD death with neck circumference according to AHI categories

From: The association of neck circumference with incident congestive heart failure and coronary heart disease mortality in a community-based population with or without sleep-disordered breathing

 

Quartiles of neck circumference

 

Q1 (low)

Q2

Q3

Q4 (high)

The overall tendency

AHI < 5#

 Subjects, n

805

655

491

283

 

 Events, n (%)

10 (1.2)

17 (2.6)

17 (3.5)

14 (4.9)

 

 Univariate Model

1 (Ref)

2.120 (0.971–4.631)

2.951 (1.351–6.445)

4.164 (1.849–9.374)

1.117 (1.049–1.189)

 Multivariate Model 1

1 (Ref)

1.622 (0.710–3.705)

2.760 (0.977–7.798)

5.480 (1.574–19.075)

1.141 (1.014–1.282)

 Multivariate Model 2

1 (Ref)

1.629 (0.714–3.717)

2.782 (0.992–7.807)

5.486 (1.624–18.527)

1.139 (1.019–1.274)

 Multivariate Model 3

1 (Ref)

1.914 (0.762–4.807)

3.427 (1.806–10.814)

5.477 (1.422–21.090)

1.134 (1.001–1.284)

AHI ≥ 5*

 Subjects, n

304

455

681

759

 

 Events, n (%)

8 (2.6)

18 (4.0)

34 (5.0)

26 (3.4)

 

 Univariate Model

1 (Ref)

1.479 (0.643–3.402)

1.886 (0.873–4.074)

1.291 (0.584–2.851)

1.013 (0.962–1.068)

 Multivariate Model 1

1 (Ref)

1.773 (0.749–4.194)

2.115 (0.858–5.215)

1.972 (0.663–5.868)

1.061 (0.979–1.150)

 Multivariate Model 2

1 (Ref)

1.643 (0.690–3.914)

1.891 (0.762–4.690)

1.735 (0.586–5.135)

1.050 (0.968–1.139)

 Multivariate Model 3

1 (Ref)

1.292 (0.504–3.309)

1.538 (0.579–4.087)

1.393 (0.472–4.538)

1.033 (0.944–1.130)

  1. Model 1 adjusted for age, gender, and BMI
  2. Model 2 adjusted for age, gender, BMI, and waist circumference
  3. Model 3 adjusted for age, gender, BMI, waist circumference, AHI, smoking status, total cholesterol, triglycerides, high-density lipoprotein, history of diabetes, and history of hypertension
  4. Results are presented as hazard ratio (95% confidence interval). CHD coronary heart disease, AHI apnoea-hypopnea index, BMI body mass index
  5. #P value for the overall tendency of neck circumference modelled as a continuous variable was 0.001, 0.028, 0.022, and 0.048 in univariate model, multivariate model 1, model 2, and model 3, respectively
  6. *P value for the overall tendency of neck circumference modelled as a continuous variable was 0.616, 0.149, 0.236, and 0.478 in univariate model, multivariate model 1, model 2, and model 3, respectively